Trial reportDeutsches Arzteblatt international2019
The Effectiveness of an Internet Intervention Aimed at Reducing Alcohol Consumption in Adults.
Trial report in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Digitally Delivered Cognitive Behavioral Interventions for Alcohol and Other Drug Use: Meta-Analysis Across Consumption and Psychosocial Outcomes.JMIR mental health · 2026Pooled it
- Understanding How and Why Alcohol Interventions Prevent and Reduce Problematic Alcohol Consumption among Older Adults: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- The tracking and reducing alcohol consumption (TRAC) intervention for veterans living with HIV/AIDS: results from a pilot randomized waitlist-controlled trial.Addiction science & clinical practice · 2025Trial
- Internet-based digital intervention to support the self-management of hypertension compared to usual care: results of the HALCYON randomized controlled trial.BMC cardiovascular disorders · 2025Trial
- Effectiveness of a digital lifestyle management intervention (levidex) to improve quality of life in people with multiple sclerosis: results of a randomized controlled trial.BMC neurology · 2024Trial
- Exploring the Role of Alcohol Metabolizing Genotypes in a 12-Week Clinical Trial of Naltrexone for Alcohol Use Disorder.Biomolecules · 2021Trial
- Results of the Optimune trial: A randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors.PloS one · 2021Trial
- Engagement With a Web-Based Intervention to Reduce Harmful Drinking: Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Healthcare effects and evidence robustness of reimbursable digital health applications in Germany: a systematic review.NPJ digital medicine · 2025Article
- The impact of increased telehealth use on the treatment of substance use disorder during the COVID-19 pandemic.SSM - population health · 2025Article
- The effects of cognitive behavioral therapy-based digital therapeutic intervention on patients with alcohol use disorder.Frontiers in psychiatry · 2025Article
- Digital Health Applications in the Area of Mental Health.Deutsches Arzteblatt international · 2023Review
- Acceptability of a digital health application to empower persons with multiple sclerosis with moderate to severe disability: single-arm prospective pilot study.BMC neurology · 2023Article
- Analysis of the Status and Future Direction for Digital Therapeutics in Children and Adolescent Psychiatry.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2023Article
- Evaluation of a Primary E-Health Intervention for People with Alcohol Use Disorder: Clinical Characteristics of Users and Efficacy.International journal of environmental research and public health · 2023Article
- Digital therapeutics in the clinic.Bioengineering & translational medicine · 2023Review
- Review
- Evidence requirements of permanently listed digital health applications (DiGA) and their implementation in the German DiGA directory: an analysis.BMC health services research · 2023Review
- [Acceptance and use of web-based interventions for alcohol abstinence].Der Nervenarzt · 2023Review
- [Evidence of positive care effects by digital health apps-methodological challenges and approaches].Innere Medizin (Heidelberg, Germany) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2012, approximately 3.38 million people in Germany had an alcoholrelated disorder. Internet interventions can help lower alcohol consumption, albeit with mostly small effect sizes. It is still unclear whether the effectiveness of programs aimed at lowering alcohol consumption can be improved by individually adjusting program content for each participant. We studied the effectiveness of Vorvida, a new cognitive-behavioral internet intervention with individual adjustment of content.
methodsA randomized controlled trial was conducted on 608 adults with problematic alcohol consumption. The primary outcome was self-reported alcohol con - sumption in the past 30 days (as determined by the Quantity-Frequency-Index, QFI) and in the past 7 days (using the Timeline Follow-Back method, TFB). The secondary outcomes were drinking behavior (binge drinking/drunkenness) and satisfaction with Vorvida. Data were collected at three time points: at baseline (t0) and three and six months later (t1, t2). Trial registration: DRKS00006104.
resultsThe intention-to-treat (ITT) analysis revealed significant differences between groups at time t1 with respect to alcohol consumption (QFI: d = 0.28; TFB: d = 0.42), binge drinking (d = 0.87), and drunkenness (d = 0.39). Satisfaction with the intervention was high (27.4 [standard deviation, SD: 5.3] out of 32 points). All effects persisted, or were stronger, at time t2. Alcohol consumption, as measured by the QFI, declined over the interval from t0 to t2 in both groups: from 63.69 g/day (SD: 61.4) to 32.67 g/day (SD: 39.78) in the intervention group, and from 61.64 g/day (SD: 58.84) to 43.75 g/day (SD: 43.68) in the control group.
conclusionVorvida was found to be effective in persons with risky, problematic alcohol consumption. Further studies should determine which elements of the program contribute most to effectiveness in routine clinical practice, and what long-term effects can be achieved.
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