ArticleThe Behavioral and brain sciences2019
Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?
Article in The Behavioral and brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Estimating survival in data-driven phenotypes of mental health symptoms and peripheral biomarkers: A prospective study.Brain, behavior, & immunity - health · 2024Article
- Moving beyond a 'one-size-fits-all' rationale in global mental health: prospects of a precision psychology paradigm.Epidemiology and psychiatric sciences · 2021Article
- It is not enough to sing its praises: the very foundations of precision psychiatry may be scientifically unsound and require examination.Psychological medicine · 2021Article
- How user knowledge of psychotropic drug withdrawal resulted in the development of person-specific tapering medication.Therapeutic advances in psychopharmacology · 2020Review
- The Digital Phenotyping Project: A Psychoanalytical and Network Theory Perspective.Frontiers in psychology · 2020Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.