ArticleBiomedical engineering online2019
Mechanical analysis of a novel biodegradable zinc alloy stent based on a degradation model.
Article in Biomedical engineering online, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 11 citations in OpenAlex.
- [Review of studies on the biomechanical modelling of the coupling effect between stent degradation and blood vessel remodeling].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundBiodegradable stents display insufficient scaffold performance due to their poor Young's Modulus. In addition, the corresponding biodegradable materials harbor weakened structures during degradation processes. Consequently, such stents have not been extensively applied in clinical therapy. In this study, the scaffold performance of a patented stent and its ability to reshape damaged vessels during degradation process were evaluated.
methodsA common stent was chosen as a control to assess the mechanical behavior of the patented stent. Finite element analysis was used to simulate stent deployment into a 40% stenotic vessel. A material corrosion model involving uniform and stress corrosion was implemented within the finite element framework to update the stress state following degradation.
resultsThe results showed that radial recoiling ratio and mass loss ratio of the patented stent is 7.19% and 3.1%, respectively, which are definitely lower than those of the common stent with the corresponding values of 22.6% and 14.1%, respectively. Moreover, the patented stent displayed stronger scaffold performance in a corrosive environment and the plaque treated with patented stents had a larger and flatter lumen.
conclusionOwing to its improved mechanical performance, the novel biodegradable zinc alloy stent reported here has high potential as an alternative choice in surgery.
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