Evidence map›Paper›PMID 30940099›Full record

ArticleBMC pregnancy and childbirth2019

Association of first trimester maternal vitamin D, ferritin and hemoglobin level with third trimester fetal biometry: result from cohort study on vitamin D status and its impact during pregnancy and childhood in Indonesia.

Raden Tina Dewi Judistiani, Tita Husnitawati Madjid, Setyorini Irianti, Yessika Adelwin Natalia, Agnes Rengga Indrati, Mohammad Ghozali, Yunia Sribudiani, Tetty Yuniati, Rizky Abdulah, Budi Setiabudiawan

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Raden Tina Dewi JudistianiPublic Health Department- Centre of Immunology Studies, Faculty of Medicine Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM.21, Kecamatan Jatinangor, Kabupaten Sumedang, Jawa Barat, 45363, Indonesia. judistiani@gmail.com.ORCID http://orcid.org/0000-0002-3265-0708
Tita Husnitawati MadjidObstetrics and Gynecology Department, Faculty of Medicine Universitas Padjadjaran, Sumedang, Indonesia.
Setyorini IriantiObstetrics and Gynecology Department, Faculty of Medicine Universitas Padjadjaran, Sumedang, Indonesia.
Yessika Adelwin NataliaPublic Health Department- Centre of Immunology Studies, Faculty of Medicine Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM.21, Kecamatan Jatinangor, Kabupaten Sumedang, Jawa Barat, 45363, Indonesia.
Agnes Rengga Indratidr Hasan Sadikin Hospital, Bandung, Indonesia.ORCID http://orcid.org/0000-0003-3923-9767
Mohammad GhozaliDepartment of Basic Medical Sciences, Faculty of Medicine Universitas Padjadjaran, Sumedang, Indonesia.
Yunia SribudianiDepartment of Basic Medical Sciences, Faculty of Medicine Universitas Padjadjaran, Sumedang, Indonesia.ORCID http://orcid.org/0000-0003-1985-3292
Tetty Yuniatidr Hasan Sadikin Hospital, Bandung, Indonesia.
Rizky AbdulahDepartment of Clinical Pharmacology, Faculty of Pharmacy Universitas Padjadjaran, Sumedang, Indonesia.ORCID http://orcid.org/0000-0002-8779-6421
Budi Setiabudiawandr Hasan Sadikin Hospital, Bandung, Indonesia.ORCID http://orcid.org/0000-0002-4842-2451
Dr. Hasan Sadikin General Hospital · IDPadjadjaran University · ID

Funding

Universitas Padjadjaran 2476/UN6.C/LT/2018
6 · The paper itself

Abstract

introductionThe role of vitamin D in placental functions and fetal growth had been addressed in many reports with conflicting results. However, such report is limited for Indonesian population. The aim of this study was to explore the association between maternal vitamin D level in the first trimester and fetal biometry in the later stage of pregnancy with adjusted OR for other determinants like hemoglobin and ferritin level.

methodsFrom July 2016 a prospective cohort study of pregnant women had begun in four cities in West Java, Indonesia. Data on maternal vitamin D, ferritin, hemoglobin level, maternal demography and fetal biometry were analyzed with linear regression.

resultsAmong 203 recruited women, 195 (96.06%) had hypovitaminosis D. One hundred fifty two (75%) were in deficient state and 43 women (21%) were in insufficient state. Women with insufficient vitamin D had the highest proportion of anemia, while women with normal vitamin D level had the highest proportion of low ferritin level. Maternal serum vitamin D showed significant associations with biparietal diameter (β = 0.141, p = 0.042) and abdominal circumference (β = 0.819, p = 0.001) after adjustment with maternal age, pre-pregnancy body mass index, parity, serum ferritin level, and hemoglobin level.

conclusionOur study suggested that sufficient maternal vitamin D level was an important factor to improve fetal growth and development.

Indexed as

AdultBiometryFemaleFerritinsFetal DevelopmentFetusHemoglobinsHumansIndonesiaLinear ModelsPregnancyPregnancy ComplicationsPregnancy Trimester, FirstPregnancy Trimester, ThirdProspective StudiesVitamin DFerritinsHemoglobinsVitamin DFerritinFetal growthHaemoglobinMaternal vitamin DPregnancy

Identifiers

PMID30940099
PMCPMC6446282
OpenAlexW2942120181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.