ArticleProceedings of the National Academy of Sciences of the United States of America1986
Assignment of the human and mouse prion protein genes to homologous chromosomes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 240 citations in OpenAlex.
- The role of cellular prion protein in immune system.BMB reports · 2023Review
- Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability.BMC biology · 2022Article
- Article
- The Three Glycotypes in the London Classification System of Sporadic Creutzfeldt-Jakob Disease Differ in Disease Duration.Molecular neurobiology · 2021Article
- Review
- PrPFrontiers in molecular neuroscience · 2021Review
- Ribosomal RNA Modulates Aggregation of theInternational journal of molecular sciences · 2020Article
- A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.PLoS pathogens · 2018Article
- The Role of the Mammalian Prion Protein in the Control of Sleep.Pathogens (Basel, Switzerland) · 2017Review
- Implications of peptide assemblies in amyloid diseases.Chemical Society reviews · 2017Review
- Prions: Beyond a Single Protein.Clinical microbiology reviews · 2016Review
- Review
- Biochemical insight into the prion protein family.Frontiers in cell and developmental biology · 2015Review
- SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells.The Journal of experimental medicine · 2013Article
- Alzheimer's disease and prion protein.Intractable & rare diseases research · 2013Review
- Roles of the cellular prion protein in the regulation of cell-cell junctions and barrier function.Tissue barriers · 2013Review
- Cellular aspects of prion replication in vitro.Viruses · 2013Review
- Is prnt a pseudogene? Identification of ram Prt in testis and ejaculated spermatozoa.PloS one · 2012Article
- Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy.Cellular and molecular neurobiology · 2007Review
- Mad cow and other maladies: update on emerging infectious diseases.Proceedings (Baylor University. Medical Center) · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles. The PrP gene was assigned to human chromosome 20 and the corresponding mouse chromosome 2 using somatic cell hybrids. In situ hybridization studies mapped the human PrP gene to band 20p12----pter. Our results should lead to studies of genetic loci syntenic with the PrP gene, which may play a role in the pathogenesis of prion diseases or other degenerative neurologic disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.