Evidence map›Paper›PMID 30939824›Full record

ArticleCells2019

The Copper(II)-Assisted Connection between NGF and BDNF by Means of Nerve Growth Factor-Mimicking Short Peptides.

Irina Naletova, Cristina Satriano, Adriana Pietropaolo, Fiorenza Gianì, Giuseppe Pandini, Viviana Triaca, Giuseppina Amadoro, Valentina Latina, Pietro Calissano, Alessio Travaglia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Diverse Functions of MultipleBiomolecules · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Peptides Derived from Growth Factors to Treat Alzheimer's Disease.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Nerve growth factor catches copper in neuronal inning.Neural regeneration research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Irina NaletovaDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. irina_naletova@yahoo.com.
Cristina SatrianoDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. csatriano@unict.it.ORCID 0000-0001-5348-5863
Adriana PietropaoloDepartment of Health Sciences, University of Catanzaro, Campus Universitario Viale Europa, 88100 Catanzaro, Italy. apietropaolo@unicz.it.
Fiorenza GianìEndocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Medical Center, University of Catania, via Palermo n. 636, 95122 Catania, Italy. fiorenza.giani@gmail.com.ORCID 0000-0002-1901-8230
Giuseppe PandiniEndocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Medical Center, University of Catania, via Palermo n. 636, 95122 Catania, Italy. gpandini@gmail.com.
Viviana TriacaMedicina Molecolare e Traslazionale "Rita Levi Montalcini", Institute of Cellular Biology and Neurobiology (IBCN), National Research Council (CNR), c/o Policlinico Umberto I, University of Rome "La Sapienza", Via del Policlinico 255, 00161 Rome, Italy. vtriaca75@gmail.com.
Giuseppina AmadoroInstitute of Translational Pharmacology (IFT), National Research Council (CNR), 00131 Rome, Italy. giusy.amadoro@gmail.com.
Valentina LatinaEuropean Brain Research Institute, Viale Regina Elena 295, 00161, 64-65, 00143 Rome, Italy. valentina.latina@libero.it.
Pietro CalissanoEuropean Brain Research Institute, Viale Regina Elena 295, 00161, 64-65, 00143 Rome, Italy. pietro.calissano@gmail.com.
Alessio TravagliaDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. alessio_travaglia@hotmail.it.
Vincenzo Giuseppe NicolettiSection of Medical Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, 95124 Catania, Italy. nicovigi@unict.it.
Diego La MendolaDepartment of Pharmacy, University of Pisa, Via Bonanno Pisano 6, 56126 Pisa, Italy. lamendola@farm.unipi.it.ORCID 0000-0002-4193-7612
Enrico RizzarelliDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. erizzarelli@unict.it.
University of Catania · ITEuropean Brain Research Institute · ITIstituto di Farmacologia Traslazionale · ITMagna Graecia University · ITPoliclinico Umberto I · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve growth factor (NGF) is a protein necessary for development and maintenance of the sympathetic and sensory nervous systems. We have previously shown that the NGF N-terminus peptide NGF(1-14) is sufficient to activate TrkA signaling pathways essential for neuronal survival and to induce an increase in brain-derived neurotrophic factor (BDNF) expression. Cu

Indexed as

Amino Acid SequenceAnimalsBrain-Derived Neurotrophic FactorCell DifferentiationCell ProliferationCell ShapeCopperCyclic AMP Response Element-Binding ProteinDimerizationEndocytosisFemaleIonophoresNerve Growth FactorPC12 CellsPhenotypePhosphorylationBrain-Derived Neurotrophic FactorCopperCyclic AMP Response Element-Binding ProteinIonophoresNerve Growth FactorReceptor, trkAAlzheimer’s diseasebrain derived neurotrophic factorcopperCREBmetal ionsnerve growth factorneurotrophinp75synapsinTrK

Identifiers

PMID30939824
PMCPMC6523629
OpenAlexW2934774093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.