ArticleInternational journal of environmental research and public health2019
Pregnant Inuit Women's Exposure to Metals and Association with Fetal Growth Outcomes: ACCEPT 2010⁻2015.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Association between maternal exposure to mercury during pregnancy and birth weight: a systematic review and meta-analysis.BMC pediatrics · 2026Pooled it
- Maternal-Fetal Exposure to Oncoelements and Their Oxidative and Epigenetic Impact on Pregnancy Outcomes.International journal of molecular sciences · 2026Review
- Health effects associated with measured contaminants in the Arctic: short communication.International journal of circumpolar health · 2024Article
- Levels and trends of metals in human populations living in the Arctic.International journal of circumpolar health · 2024Review
- Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations.International journal of circumpolar health · 2024Article
- Key recommendations and research priorities of the 2021 AMAP human health assessment.International journal of circumpolar health · 2024Article
- Early pregnancy metal levels in maternal blood and pregnancy outcomes.Scientific reports · 2024Article
- Prenatal exposure to multiple environmental chemicals and birth size.Journal of exposure science & environmental epidemiology · 2024Article
- Association between Maternal Exposure to Arsenic during Pregnancy and Risk of Preterm Birth: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2024Review
- Bread Consumption-Induced Heavy Metal Exposures and Health Risk Assessment of Pregnant Women: Turkey.Biological trace element research · 2024Article
- Sources of exposure to lead in Arctic and subarctic regions: a scoping review.International journal of circumpolar health · 2023Article
- Prenatal blood lead levels and Birth Weight: a Meta-analysis study.Journal of environmental health science & engineering · 2023Review
- Prenatal metal(loid) mixtures and birth weight for gestational age: A pooled analysis of three cohorts participating in the ECHO program.Environment international · 2022Article
- Dioxin-like Activity in Pregnant Women and Indices of Fetal Growth: The ACCEPT Birth Cohort.Toxics · 2022Article
- MercuNorth - monitoring mercury in pregnant women from the Arctic as a baseline to assess the effectiveness of the Minamata Convention.International journal of circumpolar health · 2021Article
- Serum selenium levels and asthma among seafood processing workers in Greenland.International journal of circumpolar health · 2021Article
- Assessment of DNA damage in relation to heavy metal induced oxidative stress in females with recurrent pregnancy loss (RPL).Saudi journal of biological sciences · 2021Article
- Dietary habits among men and women in West Greenland: follow-up on the ACCEPT birth cohort.BMC public health · 2021Article
- Time Trend of Persistent Organic Pollutants and Metals in Greenlandic Inuit during 1994-2015.International journal of environmental research and public health · 2021Article
- Prenatal exposure to multiple metals and birth outcomes: An observational study within the National Children's Study cohort.Environment international · 2021Observational
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental contaminants such as heavy metals are transported to the Arctic regions via atmospheric and ocean currents and enter the Arctic food web. Exposure is an important risk factor for health and can lead to increased risk of a variety of diseases. This study investigated the association between pregnant women's levels of heavy and essential metals and the birth outcomes of the newborn child. This cross-sectional study is part of the ACCEPT birth cohort (Adaption to Climate Change, Environmental Pollution, and dietary Transition) and included 509 pregnant Inuit women ≥18 years of age. Data were collected in five Greenlandic regions during 2010⁻2015. Population characteristics and birth outcomes were obtained from medical records and midwives, respectively, and blood samples were analyzed for 13 metals. Statistical analysis included one-way ANOVA, Spearman's rho, and multiple linear and logistic regression analyses. The proportion of current smokers was 35.8%. The levels of cadmium, chromium, and nickel were higher compared to reported normal ranges. Significant regional differences were observed for several metals, smoking, and parity. Cadmium and copper were significantly inversely related to birth outcomes. Heavy metals in maternal blood can adversely influence fetal development and growth in a dose⁻response relationship. Diet and lifestyle factors are important sources of toxic heavy metals and deviant levels of essential metals. The high frequency of smokers in early pregnancy is of concern, and prenatal exposure to heavy metals and other environmental contaminants in the Greenlandic Inuit needs further research.
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