Evidence map›Paper›PMID 30939100›Full record

ReviewAnnual review of neuroscience2019

Magnetic Strategies for Nervous System Control.

Michael G Christiansen, Alexander W Senko, Polina Anikeeva

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Annual review of neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07073235 narecruitingnot on this mapstarted 2025, after this paper: background citation

Neuroplastic Changes and Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Upper and Lower Extremity in Chronic Stroke Patients

TypeinterventionalSponsorDanderyd HospitalRan2025 to 2030Enrolled56ConditionsStroke, Hemiparesis After Stroke, Chronic Stroke Patients, HemiplegiaArmsIntermittent Theta Burst Stimulation, Sham Intermittent Theta Burst Stimulation
NCT07073248 narecruitingnot on this mapstarted 2025, after this paper: background citation

Neuroplastic Changes and Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Upper and Lower Extremity in Chronic Stroke Patients

TypeinterventionalSponsorDanderyd HospitalRan2025 to 2030Enrolled48ConditionsStroke, Hemiplegia, Hemiparesis After Stroke, Hand FunctionalityArmsIntermittent Theta Burst Stimulation, Sham Intermittent Theta Burst Stimulation
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Modulation of Proteinoid Electrical Spiking Activity with Magnetic Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Cellular and Molecular Effects of Magnetic Fields.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Magnetoelectric Nanodiscs Enable Wireless Transgene-Free Neuromodulation.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael G ChristiansenDepartment of Health Sciences and Technology, Swiss Federal Institute of Technology, 8093 Zürich, Switzerland.
Alexander W SenkoDepartment of Materials Science and Engineering, Research Laboratory of Electronics, and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA; email: anikeeva@mit.edu.
Polina AnikeevaDepartment of Materials Science and Engineering, Research Laboratory of Electronics, and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA; email: anikeeva@mit.edu.

Funding

Multi-Site Non-Invasive Magnetothermal Excitation and Inhibition of Deep Brain StructuresR01MH111872 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O, PRALLE, ARND · 2016 to 2019
$3.6M
NIMH NIH HHS R01 MH111872
6 · The paper itself

Abstract

Magnetic fields pass through tissue undiminished and without producing harmful effects, motivating their use as a wireless, minimally invasive means to control neural activity. Here, we review mechanisms and techniques coupling magnetic fields to changes in electrochemical potentials across neuronal membranes. Biological magnetoreception, although incompletely understood, is discussed as a potential source of inspiration. The emergence of magnetic properties in materials is reviewed to clarify the distinction between biomolecules containing transition metals and ferrite nanoparticles that exhibit significant net moments. We describe recent developments in the use of magnetic nanomaterials as transducers converting magnetic stimuli to forms readily perceived by neurons and discuss opportunities for multiplexed and bidirectional control as well as the challenges posed by delivery to the brain. The variety of magnetic field conditions and mechanisms by which they can be coupled to neuronal signaling cascades highlights the desirability of continued interchange between magnetism physics and neurobiology.

Indexed as

Magnetic FieldsAnimalsAnxietyBehavior, AnimalBrainHumansNerve NetNeuronsmagnetic fieldmagnetic nanoparticlesmagnetic stimulationmagnetoreceptionneuromodulation

Identifiers

PMID30939100
PMCPMC6617523

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.