Evidence map›Paper›PMID 30939042›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Fructose malabsorption induces cholecystokinin expression in the ileum and cecum by changing microbiota composition and metabolism.

Xufei Zhang, Alexandra Grosfeld, Edek Williams, Daniel Vasiliauskas, Sharon Barretto, Lorraine Smith, Mahendra Mariadassou, Catherine Philippe, Fabienne Devime, Chloé Melchior and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Cholecystokinin: Clinical aspects of the new biology.Journal of internal medicine · 2025
    Review
  4. Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Review
  6. Animals : an open access journal from MDPI · 2025
    Article
  7. Review
  8. Article
  9. Satiety: a gut-brain-relationship.The journal of physiological sciences : JPS · 2024
    Review
  10. Article
  11. International journal of molecular sciences · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 5 countries.

Xufei ZhangMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Alexandra GrosfeldCentre de Recherche des Cordeliers, INSERM Unité Mixte de Recherche (UMR) S1138, Sorbonne Université, Sorbonne Cités, Université Paris-Diderot (UPD), Centre National de la Recherche Scientifique (CNRS)-Instituts Hospitalo-Universitaires (IHU), Institute of Cardiometabolism and Nutrition (ICAN), Paris, France.
Edek WilliamsDepartment of Orthopedics, Rutgers University, Newark, New Jersey, USA.
Daniel VasiliauskasParis-Saclay Institute of Neuroscience, Université Paris Sud, Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, Gif-sur-Yvette, France.
Sharon BarrettoToxalim, Université de Toulouse, INRA, Toulouse, France.
Lorraine SmithToxalim, Université de Toulouse, INRA, Toulouse, France.
Mahendra MariadassouMathématiques et Informatique Appliquées du Génome à l'Environnement (MaIAGE), Unité de Recherche (UR) 1404, INRA, Jouy-en-Josas, France.
Catherine PhilippeMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Fabienne DevimeMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Chloé MelchiorINSERM Unit 1073, University of Rouen (UNIROUEN), Normandie University, Rouen, France.
Guillaume GourcerolINSERM Unit 1073, University of Rouen (UNIROUEN), Normandie University, Rouen, France.
Nathalie DourmapUNIROUEN, INSERM U1245 and Rouen University Hospital, Normandy Centre for Genomic and Personalized Medicine, Normandy University, Rouen, France.
Nicolas LapaqueMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Pierre LarraufieMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Hervé M BlottièreMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Christine HerberdenMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Philippe GerardMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Jens F RehfeldDepartment of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; and.
Ronaldo P FerrarisDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers University, Newark, New Jersey, USA.
J Christopher FrittonDepartment of Orthopedics, Rutgers University, Newark, New Jersey, USA.
Sandrine Ellero-SimatosToxalim, Université de Toulouse, INRA, Toulouse, France.
Veronique DouardMicalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
Institut National de la Recherche Agronomique · MAInserm · FRRutgers, The State University of New Jersey · USUniversité Fédérale de Toulouse Midi-Pyrénées · FRDélégation Paris 5 · FRMathématiques et Informatique Appliquées du Génome à l'Environnement · FRUniversité Paris-Sud · FRUniversity of Copenhagen · DK

Funding

Mucosal modulation by LGG and R. gnavus specific tryptophan metabolitesR01AT010243 · NCCIH · RUTGERS THE STATE UNIV OF NJ NEWARK · PI FERRARIS, RONALDO PARAOAN, GAO, NAN · 2018 to 2021
$1.6M
NCCIH NIH HHS R01 AT010243
6 · The paper itself

Abstract

Current fructose consumption levels often overwhelm the intestinal capacity to absorb fructose. We investigated the impact of fructose malabsorption on intestinal endocrine function and addressed the role of the microbiota in this process. To answer this question, a mouse model of moderate fructose malabsorption [ketohexokinase mutant (KHK)

Indexed as

AnimalsCecumCell LineCholecystokininFructokinasesFructoseGastrointestinal MicrobiomeGene Expression RegulationHumansIleumMiceMice, KnockoutCholecystokininFructokinasesFructoseketohexokinaseCCKKHKpropionate

Identifiers

PMID30939042
PMCPMC6988857
OpenAlexW2932719794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.