Evidence map›Paper›PMID 30938924›Full record

ReviewAdvanced healthcare materials2019

Protein-Engineered Functional Materials.

Yao Wang, Priya Katyal, Jin Kim Montclare

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Stimuli-triggered formation ofCell biomaterials · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Genetically Programmed Single-Component Protein Hydrogel for Spinal Cord Injury Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Article
  11. Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Contribution of the ELRs to the development of advancedFrontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yao WangDepartment of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, Brooklyn, NY, 11201, USA.
Priya KatyalDepartment of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, Brooklyn, NY, 11201, USA.
Jin Kim MontclareDepartment of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, Brooklyn, NY, 11201, USA.ORCID 0000-0001-6857-3591

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8M
Institutional Clinical and Translational Science AwardKL2TR000053 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2012 to 2014
$899k
ARO W911NF-15-1-0304NCATS NIH HHS KL2 TR000053NCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NIH HHSNSF BMAT DMR 1505214NSF-DMREF DMR 1728858NSF-MRSEC Program DMR 1420073
6 · The paper itself

Abstract

Proteins are versatile macromolecules that can perform a variety of functions. In the past three decades, they have been commonly used as building blocks to generate a range of biomaterials. Owing to their flexibility, proteins can either be used alone or in combination with other functional molecules. Advances in synthetic and chemical biology have enabled new protein fusions as well as the integration of new functional groups leading to biomaterials with emergent properties. This review discusses protein-engineered materials from the perspectives of domain-based designs as well as physical and chemical approaches for crosslinked materials, with special emphasis on the creation of hydrogels. Engineered proteins that organize or template metal ions, bear noncanonical amino acids (NCAAs), and their potential applications, are also reviewed.

Indexed as

Protein EngineeringBiocompatible MaterialsHydrogelsRecombinant ProteinsBiocompatible MaterialsHydrogelsRecombinant Proteinsbiomaterialscoiled-coilsengineered proteinsfunctional materialsrecombinant protein

Identifiers

PMID30938924
PMCPMC6703858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.