Evidence map›Paper›PMID 30938283›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Seroprevalence of Hepatitis B, Hepatitis C, and Human T-Cell Lymphotropic Virus Infections in HIV-Infected Patients in Sierra Leone.

George A Yendewa, Foday Sahr, Antonio Aguilera, Sulaiman Lakoh, Momodu Sesay, Gibrilla F Deen, Lucia Patiño, Eva Poveda, Robert A Salata

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Prevalence of viral hepatitis B and C in Sierra Leone-current knowledge and knowledge gaps: a narrative review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

George A YendewaDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Foday SahrCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Antonio AguileraDepartment of Microbiology, Complexo Hospitalario Universitario Santiago and University of Santiago, Santiago de Compostela, Spain.
Sulaiman LakohCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Momodu SesayNational HIV/AIDS Secretariat, Freetown, Sierra Leone.
Gibrilla F DeenCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Lucia PatiñoGroup of Virology and Pathogenesis, Galicia Sur Health Research Institute (Instituto de Investigación Sanitaria Galicia Sur)-Complexo Hospitalario Universitario de Vigo, SERGAS-UVigo, Vigo, Spain.
Eva PovedaGroup of Virology and Pathogenesis, Galicia Sur Health Research Institute (Instituto de Investigación Sanitaria Galicia Sur)-Complexo Hospitalario Universitario de Vigo, SERGAS-UVigo, Vigo, Spain.
Robert A SalataDivision of Infectious Diseases and HIV Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
University of Sierra Leone · SLCase Western Reserve University · USComplejo Hospitalario Universitario de Santiago · ESNational HIV/AIDS Secretariat · SLServicio Gallego de Salud · ESUniversity Hospital Complex Of Vigo · ESUniversity Hospitals of Cleveland · US

Funding

TRAINING IN GEOGRAPHIC MEDICINE &INFECTIOUS DISEASET32AI007024 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI KAZURA, JAMES WALTER · 1985 to 2020
$4.5M
NIAID NIH HHS T32 AI007024
6 · The paper itself

Abstract

HIV coinfection with hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-cell lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) is common because of shared transmission routes. There is no published data on the prevalence of these infections in people living with HIV in Sierra Leone. We conducted a cross-sectional study of 211 HIV-positive patients aged ≥ 18 years in Freetown, Sierra Leone, in November 2017. Plasma samples were analyzed using the chemiluminescent microparticle immunoassay (Architect System, Abbott ARCHITECT Analyzer, Abbott Park, IL. The majority were female (63.5%), with median age 36 years (interquartile range [IQR]: 32-44) and median CD4 count of 396 cells/µL (IQR: 214-534). Sixty patients (28.4%) were newly diagnosed and antiretroviral therapy (ART) naive; 151 patients (71.6%) were ART experienced. The prevalence of the hepatitis B surface antigen (HBsAg), total anti-hepatitis B core antibody, and anti-HCV was 21.7%, 82.9%, and 4.3%, respectively. No cases of HTLV-1 or HTLV-2 were detected. Male gender (

Indexed as

AdultCD4 Lymphocyte CountCoinfectionFemaleHepatitis BHepatitis CHIV InfectionsHTLV-II InfectionsHTLV-I InfectionsHumansMaleMiddle AgedSeroepidemiologic StudiesSierra LeoneYoung Adult

Identifiers

PMID30938283
PMCPMC6553887
OpenAlexW2934454435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.