ArticleEnvironmental microbiology2019
Feeding modes shape the acquisition and structure of the initial gut microbiota in newborn lambs.
Article in Environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 64 citations in OpenAlex.
- Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity.Journal of animal science and biotechnology · 2026Review
- Maternal Microbial Reservoirs Are Associated with Early Bacterial and Archaeal Community Assembly in Neonatal Hu Lambs.Animals : an open access journal from MDPI · 2026Article
- Rumen bacteria, feed utilization, and milk production of Damascus goats fed different levels of azolla meal.Scientific reports · 2026Article
- Host immune constraints delineate the window of microbial colonization during early development ofZoological research · 2026Article
- Maternal dietary taurine supplementation improves intestinal health of lambs via modulating gut microbiota and barrier function.Frontiers in microbiology · 2026Article
- Comparative analysis of fecal microbial community diversity between Bactrian camels and Mongolian cattle based on 16S rRNA gene sequencing.Frontiers in microbiology · 2026Article
- Comparison of Bacterial Community in the Jejunum, Ileum and Cecum of Suckling Lambs During Different Growth Stages.Microorganisms · 2025Article
- Article
- Prebiotic Xylo-Oligosaccharides Modulate the Gut Microbiome to Improve Innate Immunity and Gut Barrier Function and Enhance Performance in Piglets Experiencing Post-Weaning Diarrhoea.Microorganisms · 2025Article
- Boric Acid in Milk Replacer as a Health Enhancer and Growth Promoter for Lambs in the Suckling Period.Biological trace element research · 2025Article
- Adaptive survival strategies of rumen microbiota with solid diet deficiency in early life cause epithelial mitochondrial dysfunction.The ISME journal · 2025Article
- Article
- Life at the borderlands: microbiomes of interfaces critical to One Health.FEMS microbiology reviews · 2024Review
- Understanding the Diversity and Roles of the Ruminal Microbiome.Journal of microbiology (Seoul, Korea) · 2024Review
- Altered microbiota, antimicrobial resistance genes, and functional enzyme profiles in the rumen of yak calves fed with milk replacer.Microbiology spectrum · 2024Article
- Effects of dietary l-carnosine supplementation on the growth, intestinal microbiota, and serum metabolome of fattening lambs.Frontiers in veterinary science · 2024Article
- Antimicrobial Effects of Plant-Based Supplements on Gut Microbial Diversity in Small Ruminants.Pathogens (Basel, Switzerland) · 2023Review
- Transmission of fungi and protozoa under grazing conditions from lactating yaks to sucking yak calves in early life.Applied microbiology and biotechnology · 2023Article
- Colonization and development of the gut microbiome in calves.Journal of animal science and biotechnology · 2023Review
- Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants.Genomics, proteomics & bioinformatics · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Early gut microbial colonization is important for postnatal metabolic and immune development. However, little is known about the effects of different feeding modes (suckling versus bottle-feeding) or microbial sources on this process in farm animals. We found that suckled and bottle-fed newborn lambs had their own distinct gut microbiota. Results from 16S rRNA gene sequencing and qPCR showed that, compared with suckling, bottle feeding significantly increased the abundances of Escherichia/Shigella, Butyricicoccus, and Clostridium XlVa, while significantly decreased the abundance of Clostridium XI. The higher levels of Escherichia/Shigella in bottle-fed lambs suggest that artificial feeding may increase the number of potential pathogens and delay the establishment of the anaerobic environment and anaerobic microbes. Feeding modes also affected the direct transmission of bacteria from the mother and the environment to newborns. The SourceTracker analysis estimated that the early gut microbes of suckled lambs were mainly derived from the mother's teats (43%) and ambient air (28%); whereas those of bottle-fed lambs were dominated by bacteria from the mother's vagina (46%), ambient air (31%), and the sheep pen floor (12%). These findings advance our understanding of gut microbiota in early life and may help design techniques to improve gut microbiota and health.
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