ArticleTropical medicine & international health : TM & IH2019
Echocardiographic screening of 4107 Nigerian school children for rheumatic heart disease.
Article in Tropical medicine & international health : TM & IH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Pooled it
- Rheumatic Valvulopathy in Sub-Saharan Africa: A Cross-Sectional Study of Cameroonian Urban Schools.Global heart · 2025Article
- Rheumatic Heart Disease Burden in Africa and the Need to Build Robust Infrastructure.JACC. Advances · 2024Review
- BASELINE CLINICAL CHARACTERISTICS OF CONTEMPORARY ADULT CHRONIC RHEUMATIC HEART DISEASE IN IBADAN, NIGERIA.Annals of Ibadan postgraduate medicine · 2024Article
- The burden, prevention and care of infants and children with congenital anomalies in sub-Saharan Africa: A scoping review.PLOS global public health · 2023Article
- Rheumatic heart disease prevalence in Namibia: a retrospective review of surveillance registers.BMC cardiovascular disorders · 2022Article
- Incidence of acute rheumatic fever in northern and western Uganda: a prospective, population-based study.The Lancet. Global health · 2021Article
- A glimpse of hope: cardiac surgery in low- and middle-income countries (LMICs).Cardiovascular diagnosis and therapy · 2020Review
- The Prevalence Rates of Acute Rheumatic Fever in Africa: A Systematic Review and Meta-Analysis.Sage open pediatricsReview
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Authors and funding
23 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveEchocardiographic screening for Rheumatic Heart Disease (RHD) in Africa has revealed prevalence rates in the range of 0.5-7.4%. There are no recent large population-based studies in Nigeria. The objective of the study was to determine the prevalence of RHD in a large sample of Nigerian school children.
methodsUsing portable transthoracic echocardiography and auscultation, school children aged 5 years to 16 years in Lagos, Nigeria were screened for RHD. Diagnosis was based on the 2012 World Heart Federation echocardiographic criteria.
resultsThe 4107 children screened had mean age of 11.3 years (SD = 2.6) and 2206 (53.7%) were females. There were 38 children with abnormal echocardiograms, of which 11 (0.27%) showed RHD including two cases of definite RHD giving a prevalence of 2.7/1000 [2.9/1000 in the peri-urban, 2.4/1000 in the urban area). Echocardiography detected RHD 10 times better than auscultation [echocardiography 11 (0.27%) vs. auscultation 1 (0.02%); P = 0.003]. The remaining 27 children with abnormal echocardiograms had congenital heart defects (CHD) giving a prevalence of 6.6/1000 for CHD, a yield higher than for RHD.
conclusionPrevalence of RHD among school children in Lagos, South West Nigeria is low compared to other African countries, possibly due to better access to medical care and antibiotic treatment for infections. Our data provides evidence that RHD prevalence may vary substantially within sub-Saharan Africa, necessitating targeted population-based sampling to better understand disease burden and distribution. Further work is needed to compare within- and between-country RHD prevalence as a basis for programme planning and control efforts.
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