Evidence map›Paper›PMID 30937816›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2019

Improving the quality of care in the molecular era for children and adolescents with medulloblastoma.

T de Rojas, M Puertas, F Bautista, I de Prada, M Á López-Pino, B Rivero, C Gonzalez-San Segundo, M Gonzalez-Vicent, A Lassaletta, L Madero and 1 more

Abstract read
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In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Time to adjuvant treatment for newly diagnosed pediatric brain tumors in the molecular era: a single center retrospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

T de RojasMedical Department, European Organisation for Research and Treatment of Cancer (EORTC), Av. E. Mounier 83/11, 1200, Brussels, Belgium.
M PuertasFaculty of Medicine, Universidad Autónoma de Madrid, c/Arzobispo Morcillo 4, 28029, Madrid, Spain.
F BautistaPediatric Hematology, Oncology and Stem Cell Department, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
I de PradaPathology Department, Hospital I.U. Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
M Á López-PinoPediatric Radiology Department, Hospital I.U. Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
B RiveroPediatric Neurosurgery Department, Hospital I.U. Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
C Gonzalez-San SegundoRadiation Oncology Department, Hospital G.U. Gregorio Marañón, c/Dr. Esquerdo, 46, 28007, Madrid, Spain.
M Gonzalez-VicentPediatric Hematology, Oncology and Stem Cell Department, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
A LassalettaPediatric Hematology, Oncology and Stem Cell Department, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
L MaderoPediatric Hematology, Oncology and Stem Cell Department, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain.
L MorenoPediatric Hematology, Oncology and Stem Cell Department, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo, 65, 28009, Madrid, Spain. lucas.moreno@salud.madrid.org.ORCID http://orcid.org/0000-0002-0708-1670
Hospital Infantil Universitario Niño Jesús · ESMenéndez Pelayo International University · ESEuropean Organisation for Research and Treatment of Cancer · BEHospital General Universitario Gregorio Marañón · ESHospital Universitario de La Princesa · ESUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeElevated mortality and morbidity rates persist in pediatric patients with medulloblastoma. We present a clinical audit of a real-world cohort of patients in search for pragmatic measures to improve their management and outcome. METHODS/PATIENTS: All pediatric patients with medulloblastoma treated between 2003 and 2016 at a Spanish reference center were reviewed. In the absence of internationally accepted quality indicators (QIs) for pediatric CNS tumors, diagnostic, therapeutic, survival, and time QIs were defined and assessed.

resultsFifty-eight patients were included, 24% were younger children (< 3 years), 36% high risk (anaplastic, metastasis, or surgical residue > 1.5 cm

conclusionsThis real-world research study resulted in the development of a pragmatic set of QIs, aimed to improve clinical audits and quality of care given to children and adolescents with medulloblastoma. We hope that our findings will serve as a reference to further develop a quality assurance system with specific QIs for pediatric CNS tumors in the future and that this will ultimately improve the survival and quality of life of these patients.

Indexed as

Quality of Health CareAdolescentCerebellar NeoplasmsChildChild, PreschoolFemaleHospitals, PediatricHumansInfantMaleMedulloblastomaNeoplasm Recurrence, LocalPrognosisProgression-Free SurvivalQuality Assurance, Health CareSpainChildhoodCNS tumorsMedulloblastomaQuality assuranceQuality of careReal-world studies

Identifiers

PMID30937816
OpenAlexW2930589711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.