ReviewSurgery today2019
Etiology and management of low anterior resection syndrome based on the normal defecation mechanism.
Review in Surgery today, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- A systematic review of preoperative radiological factors associated with the development of low anterior resection syndrome (LARS).Updates in surgery · 2025Pooled it
- Systematic review: the effect of right hemicolectomy for cancer on postoperative bowel function.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Pooled it
- Patient-reported outcomes in low anterior resection syndrome: a comparison of open and robotic surgery.International journal of colorectal disease · 2026Article
- Effectiveness of pelvic floor rehabilitation in the prevention and treatment of postoperative bowel symptoms in patients with rectal cancer: a systematic review and meta-analysis of randomized controlled trials.Journal of cancer survivorship : research and practice · 2026Review
- Case Report: Quantitative and qualitative evaluation for electroacupuncture combined with moxibustion in the treatment of recalcitrant low anterior resection syndrome.Frontiers in medicine · 2026Article
- Ileostoma as a promising tool in pathophysiological study and clinical intervention: a review from bench to beside.Frontiers in immunology · 2026Review
- The Japan Society of Coloproctology Practice Guidelines for Fecal Incontinence 2024 (Revised Second Edition).Journal of the anus, rectum and colon · 2026Review
- Impact of low anterior resection syndrome after rectal surgery on sleep quality.Surgery today · 2025Article
- Review
- Long-term electroacupuncture for low anterior resection syndrome in postoperative rectal cancer patients: case reports.Frontiers in medicine · 2025Article
- The effect of robotic surgery on low anterior resection syndrome in patients with lower rectal cancer: a propensity score-matched analysis.Surgical endoscopy · 2024Article
- The role of colonic motility in low anterior resection syndrome.Frontiers in oncology · 2022Review
- The risk factors of low anterior resection syndrome after colorectal cancer surgery: A retrospective study of 566 patients in a single institution in China.Frontiers in surgery · 2022Article
- The "terminal line": a novel sign for the identification of distal mesorectum end during TME for rectal cancer.Gastroenterology report · 2022Article
- Defecation disorder and anal function after surgery for lower rectal cancer in elderly patients.Annals of gastroenterological surgery · 2022Article
- Understanding the physiology of human defaecation and disorders of continence and evacuation.Nature reviews. Gastroenterology & hepatology · 2021Review
- Single-docking robotic assisted proctectomy for rectal cancer below peritoneal reflection: a propensity score matching analysis.Annals of translational medicine · 2021Article
- Optimising functional outcomes in rectal cancer surgery.Langenbeck's archives of surgery · 2021Review
- Bowel function and quality of life after minimally invasive colectomy with D3 lymphadenectomy for right-sided colon adenocarcinoma.World journal of gastroenterology · 2020Article
- Low Anterior Resection Syndrome.Current gastroenterology reports · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle, and/or injury of the nervous supply. When the remnant rectum is small and does not function properly, an important functional role may be played by the neorectum, which is usually constructed from the left side of the colon. Hypermotility of the remnant colon may affect the manifestation of urge fecal incontinence. To develop an SPO that minimizes the risk of LARS, the anatomy and physiology of the structures involved in normal defecation need to be understood better. LARS is managed similarly to fecal incontinence. In particular, management should focus on reducing colonic motility when urge fecal incontinence is the dominant symptom.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.