Evidence map›Paper›PMID 30937425›Full record

ArticleBMC rheumatology2019

Incident gout and chronic Kidney Disease: healthcare utilization and survival.

Dena H Jaffe, Alyssa B Klein, Arriel Benis, Natalia M Flores, Hagit Gabay, Robert Morlock, Dana Y Teltsch, Jonathan Chapnick, Yair Molad, Shmuel M Giveon and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Anti-Inflammatory and Survival Benefits of Dipeptidyl Peptidase 4 Inhibitors Among Patients with Gout, T2DM Patients and Chronic Kidney Disease.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Dena H JaffeKantar Health, Ariel Sharon St 4, 52511 Ramat-Gan, Israel.ORCID 0000-0001-5134-037X
Alyssa B Klein2AstraZeneca, Medical Evidence and Observational Research Centre, 200 Orchard Ridge Drive, Gaithersburg, MD USA.
Arriel BenisClalit Research Institute, Zamenhoff 42, Floor - 1, 6435331 Tel Aviv, Israel.
Natalia M Flores4Kantar Health, Foster City, CA USA.
Hagit GabayClalit Research Institute, Zamenhoff 42, Floor - 1, 6435331 Tel Aviv, Israel.
Robert MorlockYourCareChoice, Ann Arbor, MI USA.
Dana Y Teltsch6Evidera, Waltham, MA USA.
Jonathan Chapnick7Kantar Health, Horsham, PA USA.
Yair Molad8Beilinson Hospital, Rabin Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel.
Shmuel M GiveonClalit Research Institute, Zamenhoff 42, Floor - 1, 6435331 Tel Aviv, Israel.
Becca FeldmanClalit Research Institute, Zamenhoff 42, Floor - 1, 6435331 Tel Aviv, Israel.
Maya Leventer-RobertsClalit Research Institute, Zamenhoff 42, Floor - 1, 6435331 Tel Aviv, Israel.
Clalit Health Services · ILKantar Health (United States) · USAstraZeneca (United States) · USIthaka Harbors · USMemorialCare Health System · USTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUncontrolled gout can cause significant joint and organ damage and has been associated with impairments in quality of life and high economic cost. Gout has also been associated with other comorbid diseases, such as chronic kidney disease. The current study explored if healthcare resource utilization (HRU) and survival differs between patients with incident gout in the presence or absence of chronic kidney disease (CKD).

methodsClalit Health Services (CHS) data were used to conduct a retrospective population-based cohort study of incident gout between 1/1/2006-31/12/2009. Incident cases of gout were identified and stratified by CKD status and by age group (< 55 and 55+ years). CKD status was defined as a pre-existing diagnosis of chronic kidney disease, chronic renal failure, kidney transplantation, or dialysis at index date. Demographic and clinical characteristics, as well as healthcare resource use, were reported.

resultsA total of 12,940 incident adult gout patients, with (

conclusionsThe current study suggests important differences exist in patient characteristics and outcomes among patients with gout and CKD. Healthcare utilization differed between sub-populations, age and comorbidities, over the study period and the 5-year mortality risk was higher for gout patients with CKD, regardless of age. Future work should explore factors associated with these outcomes and barriers to gout control in order to enhance patient management among this high-risk subgroup.

Indexed as

Chronic kidney diseaseGoutHealthcare utilizationSurvival

Identifiers

PMID30937425
PMCPMC6425669
OpenAlexW2940176361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.