Evidence map›Paper›PMID 30937312›Full record

ArticleBioMed research international2019

Characteristics, Risk Factors, and Adverse Outcomes of Hyperkalemia in Acute-on-Chronic Liver Failure Patients.

Jun-Jun Cai, Kai Wang, Hui-Qing Jiang, Tao Han

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06857682 (Haematological Indices as a Prognostic Predictor Among Patients With Acute on Top of Chronic Liver Cell Failure), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06857682 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Haematological Indices as a Prognostic Predictor Among Patients With Acute on Top of Chronic Liver Cell Failure

TypeobservationalSponsorAssiut UniversityRan2024 to 2027Enrolled170ConditionsAcute on Top of Chronic Liver Cell Failure
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jun-Jun CaiDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, Shijiazhuang, China.ORCID 0000-0001-8724-9498
Kai WangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Hui-Qing JiangDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, Shijiazhuang, China.ORCID 0000-0002-5235-1457
Tao HanDepartment of Hepatology, Tianjin Third Central Hospital, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Tianjin, China.ORCID 0000-0003-4216-6968
Hebei Medical University · CNBeijing University of Chinese Medicine · CNTianjin Third Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperkalemia is a serious complication in cirrhotic patients. However, the clinical characteristics, risk factors, and its impact on the outcomes in acute-on-chronic liver failure (ACLF) patients remain unclear.

methodsWe retrospectively recruited 650 ACLF patients in this study. The risk factors associated with hyperkalemia and its relationship with 90-day mortality were analyzed using multivariable regression models.

resultsAmong 650 patients with ACLF, 12.2% (79/650) had hyperkalemia during hospitalization. Higher admission serum potassium levels and the presence of acute kidney injury (AKI) were independent risk factors for hyperkalemia. The prevalence rates of hyperkalemia in patients with and without AKI were 23.6% and 4.6%, respectively (

conclusionsHyperkalemia increases the 90-day mortality in ACLF patients; hyperkalemia is associated with AKI. Patients with both AKI and hyperkalemia had the worst outcome.

Indexed as

Acute Kidney InjuryAcute-On-Chronic Liver FailureBlood Urea NitrogenCreatinineFemaleHumansHyperkalemiaKidneyMaleMiddle AgedPotassiumRisk FactorsSodiumSurvival AnalysisCreatininePotassiumSodium

Identifiers

PMID30937312
PMCPMC6415283
OpenAlexW2916204567

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.