Evidence map›Paper›PMID 30936915›Full record

ReviewNeural plasticity2019

Brain Functional Reserve in the Context of Neuroplasticity after Stroke.

Jan Dąbrowski, Anna Czajka, Justyna Zielińska-Turek, Janusz Jaroszyński, Marzena Furtak-Niczyporuk, Aneta Mela, Łukasz A Poniatowski, Bartłomiej Drop, Małgorzata Dorobek, Maria Barcikowska-Kotowicz and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Recovery from disorders of consciousness: Lesions and GABAergic modulation in a biologically inspired spiking neural network.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Neural repair mechanisms after ischemic stroke.Inflammation and regeneration · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jan DąbrowskiDepartment of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.ORCID 0000-0003-0483-1373
Anna CzajkaDepartment Neurology, Central Clinical Hospital of the Ministry of the Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland.
Justyna Zielińska-TurekDepartment Neurology, Central Clinical Hospital of the Ministry of the Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland.
Janusz JaroszyńskiDepartment of Public Health, 2nd Faculty of Medicine, Medical University of Lublin, Chodźki 1, 20-093 Lublin, Poland.
Marzena Furtak-NiczyporukDepartment of Public Health, 2nd Faculty of Medicine, Medical University of Lublin, Chodźki 1, 20-093 Lublin, Poland.
Aneta MelaDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CePT), Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland.
Łukasz A PoniatowskiDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CePT), Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland.ORCID 0000-0003-4202-7984
Bartłomiej DropDepartment of Information Technology and Medical Statistics, Faculty of Health Sciences, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.
Małgorzata DorobekDepartment Neurology, Central Clinical Hospital of the Ministry of the Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland.
Maria Barcikowska-KotowiczDepartment of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Andrzej ZiembaDepartment of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.ORCID 0000-0002-9354-5936
Central Clinical Hospital · PLMedical University of Lublin · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is the second cause of death and more importantly first cause of disability in people over 40 years of age. Current therapeutic management of ischemic stroke does not provide fully satisfactory outcomes. Stroke management has significantly changed since the time when there were opened modern stroke units with early motor and speech rehabilitation in hospitals. In recent decades, researchers searched for biomarkers of ischemic stroke and neuroplasticity in order to determine effective diagnostics, prognostic assessment, and therapy. Complex background of events following ischemic episode hinders successful design of effective therapeutic strategies. So far, studies have proven that regeneration after stroke and recovery of lost functions may be assigned to neuronal plasticity understood as ability of brain to reorganize and rebuild as an effect of changed environmental conditions. As many neuronal processes influencing neuroplasticity depend on expression of particular genes and genetic diversity possibly influencing its effectiveness, knowledge on their mechanisms is necessary to understand this process. Epigenetic mechanisms occurring after stroke was briefly discussed in this paper including several mechanisms such as synaptic plasticity; neuro-, glio-, and angiogenesis processes; and growth of axon.

Indexed as

Stroke RehabilitationBrainHumansNeuronal PlasticityRecovery of FunctionStroke

Identifiers

PMID30936915
PMCPMC6415310
OpenAlexW2920403041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.