Evidence map›Paper›PMID 30936873›Full record

ArticleFrontiers in immunology2019

Glucocorticoid Receptor-Deficient Foxp3

Lourdes Rocamora-Reverte, Selma Tuzlak, Laura von Raffay, Marcel Tisch, Heidi Fiegl, Mathias Drach, Holger M Reichardt, Andreas Villunger, Denise Tischner, G Jan Wiegers

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

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  9. Characterization of Regulatory T Cells in Patients Infected byTropical medicine and infectious disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Lourdes Rocamora-ReverteDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Selma TuzlakDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Laura von RaffayDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Marcel TischDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Heidi FieglDepartment of Obstetrics and Gynecology, Innsbruck University Hospital, Innsbruck, Austria.
Mathias DrachDepartment of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Holger M ReichardtInstitute for Cellular and Molecular Immunology, University Medical Center Göttingen, Göttingen, Germany.
Andreas VillungerDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Denise TischnerDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
G Jan WiegersDivision of Developmental Immunology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATCeMM Research Center for Molecular Medicine · ATUniversity Hospital Innsbruck · ATUniversity Hospital of Zurich · CHUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the immune system increases systemic adrenal-derived glucocorticoid (GC) levels which downregulate the immune response as part of a negative feedback loop. While CD4

Indexed as

Adoptive TransferAnimalsAntibodies, AntinuclearCD4-Positive T-LymphocytesCell SurvivalColitisCytokinesDisease Models, AnimalFemaleForkhead Transcription FactorsGene Knockdown TechniquesGlucocorticoidsInflammatory Bowel DiseasesLymphocyte ActivationMaleMiceAntibodies, AntinuclearCytokinesForkhead Transcription FactorsFoxp3 protein, mouseGlucocorticoidsReceptors, GlucocorticoidFoxp3glucocorticoidglucocorticoid receptorregulatory T cellsuppressiontransfer colitis

Identifiers

PMID30936873
PMCPMC6431616
OpenAlexW2921178159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.