Evidence map›Paper›PMID 30936776›Full record

ArticleMediators of inflammation2019

Hepcidin and Iron Homeostasis in Patients with Subacute Thyroiditis and Healthy Subjects.

Aleksandra Hernik, Ewelina Szczepanek-Parulska, Dorota Filipowicz, Agata Czarnywojtek, Elżbieta Wrotkowska, Lucyna Kramer, Alina Urbanovych, Marek Ruchała

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aleksandra HernikDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.
Ewelina Szczepanek-ParulskaDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.ORCID 0000-0003-3661-3274
Dorota FilipowiczDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.ORCID 0000-0002-2205-4558
Agata CzarnywojtekDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.
Elżbieta WrotkowskaDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.
Lucyna KramerDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, Poland.
Alina UrbanovychDepartment of Endocrinology, Lviv National Medical University, Ukraine.
Marek RuchałaDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.
Poznan University of Medical Sciences · PLDanylo Halytsky Lviv National Medical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHepcidin is an acute-phase protein involved also in regulation of iron homeostasis. The aim of the study was to prospectively assess for the first time the hepcidin

methodsOut of 40 patients with SAT initially recruited, restrictive inclusion criteria fulfilled 21 subjects aged 45 ± 10 years and 21 healthy control subjects (CS). Hepcidin

resultsThe median hepcidin

conclusionsSAT is accompanied by a significant increase in hepcidin, which reflects an acute-phase inflammatory process. Parameters of iron homeostasis improved significantly while inflammatory indices got lower following recovery. The potential role of hepcidin as a predictive factor of the risk of SAT relapse needs to be assessed in studies on larger groups of SAT patients.

Indexed as

AdultFemaleHepcidinsHomeostasisHumansIronMaleMiddle AgedProspective StudiesThyroiditis, SubacuteHepcidinsIron

Identifiers

PMID30936776
PMCPMC6415316
OpenAlexW2920429105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.