Evidence map›Paper›PMID 30936749›Full record

ArticleCancer management and research2019

Etiology and management of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma.

Jiabin Zhan, Shuai Zhang, Xin Wei, Yihui Fu, Jing Zheng

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06348485 (Massive Nasal Bleeding in Patients With Nasopharyngeal Carcinoma Received Curative Radiotherapy), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06348485 completednot on this map

Massive Nasal Bleeding in Patients With Nasopharyngeal Carcinoma Received Curative Radiotherapy

TypeobservationalSponsorTaichung Veterans General HospitalRan1994 to 2024Enrolled1,327ConditionsNasopharyngeal Carcinoma Patients Treated With Curative RadiotherapyArmsPatients without massive nasal bleeding, Patients with massive nasal bleeding
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Clinical and MRI risk factors predicting post-irradiation carotid blowout syndrome in patients with nasopharyngeal cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Retrospective analysis of massive epistaxis and pseudoaneurysms in nasopharyngeal carcinoma after radiotherapy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Review
  6. Article
  7. Review
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiabin ZhanDepartment of Otolaryngology, Hainan General Hospital, Haikou 570311, Hainan, China, hnweking@sina.com.
Shuai ZhangDepartment of Radiation Oncology, Hainan General Hospital, Haikou 570311, Hainan Province, China, 46370976@qq.com.
Xin WeiDepartment of Otolaryngology, Hainan General Hospital, Haikou 570311, Hainan, China, hnweking@sina.com.
Yihui FuDepartment of Respiratory Medicine, Hainan General Hospital, Haikou 570311, Hainan Province, China.
Jing ZhengDepartment of Otolaryngology, Hainan General Hospital, Haikou 570311, Hainan, China, hnweking@sina.com.
Hainan General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the etiology of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma (NPC) and evaluate the relevant management and rescue approaches.

methodsSeventeen cases of nasopharyngeal hemorrhage caused by radiotherapy of NPC, treated between January 2015 and March 2018, were retrospectively analyzed to study the etiology of nasopharyngeal hemorrhage. The management and rescue strategies, including anterior and posterior nostril packing, endoscopic nasopharynx electrocoagulation, and digital subtraction angiography embolization, were assessed for their effectiveness.

resultsNasopharynx hemorrhage after radiotherapy of NPC was mainly associated with erosion of the internal carotid artery or maxillary artery by the tumor. Among the 17 cases, 11 patients were treated by digital subtraction arterial angiography embolization, and 3 were treated by endoscopic nasopharynx electrocoagulation. Overall, 13 patients survived, while 4 died.

conclusionAnterior and posterior nostril packing, endoscopic nasopharynx electrocoagulation, and digital subtraction angiography embolization are suitable for treating nasopharyngeal hemorrhage. However, effective hemostasis depends on early identification of the bleeding vessels.

Indexed as

nasopharyngeal carcinoma (NPC)nasopharyngeal hemorrhageprognosisradiotherapy

Identifiers

PMID30936749
PMCPMC6421873
OpenAlexW2920951501

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.