Evidence map›Paper›PMID 30936712›Full record

Observational studyVascular health and risk management2019

Characteristics of patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) from the ARIAM-SEMICYUC registry: development of a score for predicting MINOCA.

Daniel Ballesteros-Ortega, Oscar Martínez-González, Rafael Blancas Gómez-Casero, Manuel Quintana-Díaz, Eva de Miguel-Balsa, Carmen Martín-Parra, Blanca López-Matamala, Miriam Chana-García, M Ángeles Alonso-Fernández, Madián Manso-Álvarez

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Vascular health and risk management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel Ballesteros-OrtegaCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Oscar Martínez-GonzálezCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Rafael Blancas Gómez-CaseroCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Manuel Quintana-DíazCritical Care Department, Hospital Universitario La Paz, 28046 Madrid, Spain.
Eva de Miguel-BalsaCritical Care Department, Hospital General Universitario de Elche, 03203 Elche, Alicante, Spain.
Carmen Martín-ParraCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Blanca López-MatamalaCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Miriam Chana-GarcíaCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
M Ángeles Alonso-FernándezCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.
Madián Manso-ÁlvarezCritical Care Department, Hospital Universitario del Tajo, CP 28300, Aranjuez, Spain, rafael.blancas@salud.madrid.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myocardial infarction (AMI) with no evidence of relevant stenosis of the coronary artery, known as myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA), has a prevalence of up to 14%. The various causes of MINOCA lead to damage of the myocardium, and there are marked differences in diagnoses, prognoses, and treatments. Although the number of patients affected is considerable owing to the high prevalence of acute coronary syndrome (ACS), the causes of MINOCA have received little attention with the result that some patients may not receive appropriate treatment. Awareness of this disease among clinicians has started only to improve since the beginning of the current century. The aim of this study was to develop a score that enables patients with MINOCA to be distinguished from patients with MI with coronary artery disease (MI-CAD) and thus to facilitate appropriate diagnosis and therapy. PATIENTS AND

methodsA multicenter observational cohort study was designed. All patients aged ≥18 years from the ARIAM-SEMICYUC (Analysis of Delay in AMI-Spanish Society of Intensive Care Medicine and Coronary Unit) registry, diagnosed with AMI, and admitted to critical care units or coronary care units (CCUs) were included. Patients were classified into two groups: MINOCA, comprising patients with no significant lesions on angiography, and MI-CAD, comprising patients with lesions of the coronary artery tree.

resultsA score based on standard variables to assess the probability of MINOCA on admission was designed, showing a maximum value corresponding to a 40% probability of MINOCA. The discriminative power of the model was 0.756 (

conclusionPatients with MINOCA constitute a population that differs from other patients with AMI. Their differential characteristics require a certain diagnostic effort to align therapy with the disease causing the ischemic event. This score could prove useful in establishing additional diagnostic procedures.

Indexed as

Decision Support TechniquesAgedAge FactorsBiomarkersCoronary AngiographyCoronary Artery DiseaseCoronary StenosisDiagnosis, DifferentialFemaleHumansMaleMiddle AgedMyocardial InfarctionPredictive Value of TestsPrognosisRegistriesBiomarkersTroponinacute myocardial infarctioncoronary syndromeMINOCAnonobstructive coronary diseasescore

Identifiers

PMID30936712
PMCPMC6422404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.