ArticleInternational journal of nanomedicine2019
Biosynthesis, characterization, and anticancer effect of plant-mediated silver nanoparticles using
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 101 citations in OpenAlex.
- Silver Nanoparticles (AgNPs) as a Double-Edged Sword: Synthesis, Factors Affecting, Mechanisms of Toxicity and Anticancer Potentials-An Updated Review till March 2025.Biological trace element research · 2026Review
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- Updated Review of Metal Nanoparticles Fabricated by Green Chemistry Using Natural Extracts: Biosynthesis, Mechanisms, and Applications.Bioengineering (Basel, Switzerland) · 2024Review
- Silver Nanoparticles: Synthesis, Structure, Properties and Applications.Nanomaterials (Basel, Switzerland) · 2024Review
- Green synthesis of silver nanoparticle prepared with Ocimum species and assessment of anticancer potential.Scientific reports · 2024Article
- Phyco-synthesis of silver nanoparticles by environmentally safe approach and their applications.Scientific reports · 2024Article
- The Antibacterial Effectiveness of Citrullus lanatus-Mediated Stannous Nanoparticles on Streptococcus mutans.Cureus · 2023Article
- Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy.Cells · 2023Review
- Antifungal Activity ofJournal of functional biomaterials · 2023Article
- The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future?Life (Basel, Switzerland) · 2023Review
- Synthesis of Green Engineered Silver Nanoparticles throughAntibiotics (Basel, Switzerland) · 2022Article
- Novel Antibacterial, Cytotoxic and Catalytic Activities of Silver Nanoparticles Synthesized from Acidophilic Actinobacterial SL19 with Evidence for Protein as Coating Biomolecule.Journal of microbiology and biotechnology · 2022Article
- Nanostructured Antibiotics and Their Emerging Medicinal Applications: An Overview of Nanoantibiotics.Antibiotics (Basel, Switzerland) · 2022Review
- Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles.Scientific reports · 2022Article
- Antibacterial, Antifungal, and Antioxidant Activities of Silver Nanoparticles Biosynthesized fromAntioxidants (Basel, Switzerland) · 2021Article
- Biomedical Applications of Chinese Herb-Synthesized Silver Nanoparticles by Phytonanotechnology.Nanomaterials (Basel, Switzerland) · 2021Review
- Green Metallic Nanoparticles for Cancer Therapy: Evaluation Models and Cancer Applications.Pharmaceutics · 2021Review
- Cytotoxicity against human breast carcinoma cells of silver nanoparticles biosynthesized using Capsosiphon fulvescens extract.Bioprocess and biosystems engineering · 2021Article
- Phyto-fabrication, purification, characterisation, optimisation, and biological competence of nano-silver.IET nanobiotechnology · 2021Article
- Current Advances inFrontiers in pharmacology · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTremendous growth in nanotechnology has opened up new frontiers in fundamental and applied aspects, including the synthesis of nanoscale matter and understanding/utilizing its exotic physicochemical and optoelectronic properties. Green-synthesis methods employing either biological microorganisms or plant extracts have emerged as a simple and alternative to chemical synthesis.
methodsIn our present study, we aimed to synthesize silver nanoparticles (AgNPs) in combination with an aqueous extract of
resultsIn our results, ultraviolet-visible spectroscopy revealed a near-absorbance peak at 450 nm, which confirmed the AgNP synthesis. The crystalline nature of the AgNPs was revealed with X-ray diffraction. Transmission electron-microscopy analysis showed spherically dispersed nanoparticles of 6-45 nm diameter. We analyzed the elementary mechanism across A549 lung carcinoma cells ahead of treatment with doses of CC-AgNPs (10 µg/mL and 25 µg/mL). The antiproliferative effect of CC-AgNPs revealed a significant decline in cell viability. Antibacterial assays with both Gram-negative (
conclusionFurthermore, CC-AgNPs regulated apoptosis using the intrinsic pathway to inhibit A549-cell proliferation. Proliferation migration and invasion were notably inhibited by CC-AgNPs, which promoted apoptosis in lung adenocarcinoma cells by regulating the apoptotic pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.