Evidence map›Paper›PMID 30936694›Full record

ArticleInternational journal of nanomedicine2019

NLRP3 inflammasome, oxidative stress, and apoptosis induced in the intestine and liver of rats treated with titanium dioxide nanoparticles: in vivo and in vitro study.

Ebrahim Abbasi-Oshaghi, Fatemeh Mirzaei, Mona Pourjafar

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 108 citations in OpenAlex.

  1. Review
  2. Food-grade TiOJournal of nanobiotechnology · 2026
    Article
  3. Article
  4. Mitigation of nicotine-induced podocyte injury through inhibition of thioredoxin interacting protein.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Hepatotoxicity of titanium dioxide nanoparticles.Journal of applied toxicology : JAT · 2025
    Review
  9. Article
  10. How TiOInternational journal of nanomedicine · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Therapeutic Candidates for Alzheimer's Disease: Saponins.International journal of molecular sciences · 2023
    Review
  17. Article
  18. [Effects of titanium dioxide nanoparticles on circRNA expression profiles in human hepatocellular carcinoma cells HepG2].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ebrahim Abbasi-OshaghiResearch Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran, a.oshaghi@umsha.ac.ir.
Fatemeh MirzaeiNeurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran, a.oshaghi@umsha.ac.ir.
Mona PourjafarStudent Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the effects of titanium dioxide nanoparticles (TiO

methodsMale rats were divided into four groups as follows: 1) control rats, 2) control rats that orally received 10 mg/kg TiO

resultsTiO

conclusionTiO

Indexed as

ApoptosisOxidative StressAnimalsAntioxidantsCaco-2 CellsCatalaseGlutathioneGlutathione PeroxidaseHep G2 CellsHumansInflammasomesInflammationIntestinesLiverMaleNanoparticlesAntioxidantsCatalaseGlutathioneGlutathione PeroxidaseInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinSuperoxide DismutaseTitaniumtitanium dioxidecaco-2 cellsgene expressionhepg2 cellsrat

Identifiers

PMID30936694
PMCPMC6421874
OpenAlexW2921595616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.