Evidence map›Paper›PMID 30936690›Full record

Trial reportInternational journal of chronic obstructive pulmonary disease2019

Blood pressure response to exposure to moderate altitude in patients with COPD.

Esther I Schwarz, Tsogyal D Latshang, Michael Furian, Deborah Flück, Sebastian Segitz, Severine Müller-Mottet, Silvia Ulrich, Konrad E Bloch, Malcolm Kohler

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01875133 (Effect of Altitude on Exercise Performance of Patients With Chronic Obstructive Lung Disease), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01875133 nacompletednot on this map

Effect of Altitude on Exercise Performance of Patients With Chronic Obstructive Lung Disease

TypeinterventionalSponsorUniversity of ZurichRan2013 to 2013Enrolled50ConditionsChronic Obstructive Pulmonary Disease (COPD)Armsaltitude exposure
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Revealing lncRNA Biomarkers Related to Chronic Obstructive Pulmonary Disease Based on Bioinformatics.International journal of chronic obstructive pulmonary disease · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Esther I SchwarzDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Tsogyal D LatshangDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Michael FurianDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Deborah FlückDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Sebastian SegitzDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Severine Müller-MottetDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Silvia UlrichDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Konrad E BlochDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Malcolm KohlerDepartment of Pulmonology and Sleep Disorders Centre, University Hospital of Zurich, Zurich, Switzerland, malcolm.kohler@usz.ch.
Kohler (New Zealand) · NZUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/increased BPV and high cardiovascular risk. The aim of this study was to evaluate the effect of short-term exposure to moderate altitude on BP and measures of cardiovascular autonomic regulation in COPD patients. Materials and methods: Continuous morning beat-to-beat BP was noninvasively measured with a Finometer Results: Thirty-seven patients with moderate to severe COPD (mean±SD age 64±6 years, FEV Conclusion: Exposure of COPD patients to moderate altitude is associated with a clinically relevant increase in BP, which seems to be related to autonomic dysregulation. Clinical trial registration: ClinicalTrials.gov (NCT01875133).

Indexed as

AltitudeBaroreflexBlood PressureAdolescentAdultAgedAutonomic Nervous SystemCardiovascular SystemCircadian RhythmFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPulmonary Disease, Chronic Obstructivebaroreflex sensitivityblood pressure variabilityCOPDhypobaric hypoxia

Identifiers

PMID30936690
PMCPMC6421900
OpenAlexW2921453194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.