Evidence map›Paper›PMID 30936652›Full record

ArticleVeterinary world2019

Infection kinetics and antibody responses in Deccani sheep during experimental infection and superinfection with bluetongue virus serotypes 4 and 16.

Kalyani Putty, Abdul Muzeer Shaik, Shaik Jahangeer Peera, Y Narasimha Reddy, P P Rao, Sunil R Patil, M Shreekanth Reddy, B Susmitha, J Shiva Jyothi

Abstract read
In one paragraph

Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Increased Virulence ofViruses · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kalyani PuttyDepartment of Veterinary Microbiology and Veterinary Biotechnology, College of Veterinary Science, Rajendranagar, P V Narasimha Rao Telangana Veterinary University, Hyderabad, Telangana, India.
Abdul Muzeer ShaikVeterinary Dispensary, Department of Animal Husbandry, Labbipet, Vijayawada, Andhra Pradesh, India.
Shaik Jahangeer PeeraVeterinary Dispensary, Department of Animal Husbandry, Labbipet, Vijayawada, Andhra Pradesh, India.
Y Narasimha ReddyDepartment of Veterinary Microbiology and Veterinary Biotechnology, College of Veterinary Science, Rajendranagar, P V Narasimha Rao Telangana Veterinary University, Hyderabad, Telangana, India.
P P RaoBiovet, KIADB Industrial Area, Malur, Karnataka, India.
Sunil R PatilDepartment of Veterinary Microbiology and Veterinary Biotechnology, College of Veterinary Science, Rajendranagar, P V Narasimha Rao Telangana Veterinary University, Hyderabad, Telangana, India.
M Shreekanth ReddyDepartment of Veterinary Microbiology and Veterinary Biotechnology, College of Veterinary Science, Rajendranagar, P V Narasimha Rao Telangana Veterinary University, Hyderabad, Telangana, India.
B SusmithaElla Foundation, Genome Valley, Shamirpet, Hyderabad, Telangana, India.
J Shiva JyothiDepartment of Veterinary Microbiology and Veterinary Biotechnology, College of Veterinary Science, Rajendranagar, P V Narasimha Rao Telangana Veterinary University, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe current study was designed to understand the infection kinetics and antibody responses of major circulating serotypes of bluetongue virus (BTV) in India, i.e., BTV-4 and BTV-16 through experimental infection and superinfection of Deccani sheep, a popular breed of sheep found in the southern states of India. MATERIALS AND

methodsExperimental infection with 10

resultsCertain interesting findings have been made in the course of experimental infection, such as prominent signs of infection in BTV-4 infection, mild or no clinical signs in BTV-16-infected and superinfected animals, and non-seroconversion of one of the BTV-16-superinfected animals. In addition, BTV was isolated from infected sheep in all the experimental conditions except BTV-16 superinfection. Furthermore, it was observed that immune response in the form of type-specific antibodies was slower with BTV-16 superinfection.

conclusionSuperinfection of a sheep with more than one serotype of BTV is a common phenomenon in BT endemic countries like India. Such situation was replicated in an experimental infection in the current study, and the findings to our knowledge are first of a kind and are likely to aid in unfolding the newer aspects of BTV pathogenesis and virulence.

Indexed as

bluetonguebluetongue virus-16bluetongue virus-4infection kineticssuperinfection

Identifiers

PMID30936652
PMCPMC6431802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.