Eliminating protective autophagy in KRAS-mutant cancers.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies.Signal transduction and targeted therapy · 2023
   Review
2. Emerging roles of RNA binding proteins in intervertebral disc degeneration and osteoarthritis.Orthopaedic surgery · 2023
   Review
3. Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy.Cell death & disease · 2023
   Article
4. Farnesoid X receptor activation inhibits pancreatic carcinogenesis.Biochimica et biophysica acta. Molecular basis of disease · 2023
   Article
5. Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models.Journal of translational medicine · 2022
   Article
6. Next-generation immunotherapy for pancreatic ductal adenocarcinoma: navigating pathways of immune resistance.Cancer metastasis reviews · 2021
   Review
7. Recent advances in cancer immunotherapy.Discover oncology · 2021
   Review
8. Concomitant MEK and Cyclin Gene Alterations: Implications for Response to Targeted Therapeutics.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
   Article
9. The Role of Decorin and Biglycan Signaling in Tumorigenesis.Frontiers in oncology · 2021
   Review
10. Targeting Autophagy in Breast Cancer.International journal of molecular sciences · 2020
    Review
11. Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma.Cells · 2020
    Review
12. Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.Cell death & disease · 2020
    Article
13. Berberine Induces Autophagic Cell Death in Acute Lymphoblastic Leukemia by Inactivating AKT/mTORC1 Signaling.Drug design, development and therapy · 2020
    Article

Corrections and comments

• Comment on
  Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.2019
• Comment on
  Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.2019

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as