Evidence map›Paper›PMID 30936342›Full record

ArticleBMJ case reports2019

A rare mimic of acute stroke: rapidly progressing Miller-Fisher Syndrome to acute motor and sensory axonal neuropathy variant of Guillain-Barre Syndrome.

Lennie Lynn Chua de Castillo, Jose Danilo Bengzon Diestro, Katrina Hannah Dizon Ignacio, Paul Matthew Dimaguila Pasco

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lennie Lynn Chua de CastilloDepartment of Neurosciences, University of the Philippines Manila College of Medicine and Philippine General Hospital, Manila, Philippines.ORCID http://orcid.org/0000-0003-3263-1002
Jose Danilo Bengzon DiestroDepartment of Neurosciences, University of the Philippines Manila College of Medicine and Philippine General Hospital, Manila, Philippines.ORCID http://orcid.org/0000-0001-8450-2021
Katrina Hannah Dizon IgnacioDepartment of Neurosciences, University of the Philippines Manila College of Medicine and Philippine General Hospital, Manila, Philippines.
Paul Matthew Dimaguila PascoDepartment of Neurosciences, University of the Philippines Manila College of Medicine and Philippine General Hospital, Manila, Philippines.
Philippine General Hospital · PHYahoo (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ophthalmoplegia, ataxia and areflexia characterise the clinical triad of Miller-Fisher Syndrome (MFS). When the disease presents acutely, it can mimic posterior circulation stroke. We describe a case of an adult patient presenting with sudden dizziness, diplopia, vomiting, and loss of balance. She was initially managed as a case of a brainstem stroke, but the progression of craniopathies without deterioration in sensorium coupled with areflexia clinched the diagnosis of MFS two days into her admission. On the third day, her MFS progressed rapidly to acute motor and sensory axonal neuropathy (AMSAN) variant of Guillain-Barre Syndrome, a rare occurrence in patients with MFS, with only four reported cases including our own. Among the four cases, ours is the only one still non-ambulatory eight months after the initial onset of symptoms. The case highlights the importance of early recognition of MFS in patients with ophthalmoplegia and ataxia despite initially normal reflexes.

Indexed as

Diagnosis, DifferentialDiplopiaDisease ProgressionDizzinessFemaleGuillain-Barre SyndromeHumansImmunoglobulins, IntravenousImmunologic FactorsMagnetic Resonance ImagingMiddle AgedMiller Fisher SyndromeNeurologic ExaminationPostural BalanceRecovery of FunctionTime FactorsImmunoglobulins, IntravenousImmunologic Factorsacute motor and sensory axonal neuropathyGuillain-Barre SyndromeMiller-Fisher Syndromestroke

Identifiers

PMID30936342
PMCPMC6453342
OpenAlexW2931313760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.