Evidence map›Paper›PMID 30936248›Full record

ArticlePlant physiology2019

Pinstatic Acid Promotes Auxin Transport by Inhibiting PIN Internalization.

Akihiro Oochi, Jakub Hajny, Kosuke Fukui, Yukio Nakao, Michelle Gallei, Mussa Quareshy, Koji Takahashi, Toshinori Kinoshita, Sigurd Ramans Harborough, Stefan Kepinski and 4 more

Open access · greenAbstract read
In one paragraph

Article in Plant physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Fourteen Stations of Auxin.Cold Spring Harbor perspectives in biology · 2022
    Review
  9. Review
  10. Article
  11. Chemical Biology in Auxin Research.Cold Spring Harbor perspectives in biology · 2021
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Akihiro OochiDepartment of Biochemistry, Okayama University of Science, Okayama 700-0005, Japan.
Jakub HajnyInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.ORCID 0000-0003-2140-7195
Kosuke FukuiDepartment of Biochemistry, Okayama University of Science, Okayama 700-0005, Japan.
Yukio NakaoDepartment of Biochemistry, Okayama University of Science, Okayama 700-0005, Japan.
Michelle GalleiInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Mussa QuareshySchool of Life Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom.ORCID 0000-0001-8115-9803
Koji TakahashiGraduate School of Science, Nagoya University, Chikusa, Nagoya, 464-8602 Japan.ORCID 0000-0001-5438-7624
Toshinori KinoshitaGraduate School of Science, Nagoya University, Chikusa, Nagoya, 464-8602 Japan.ORCID 0000-0001-7621-1259
Sigurd Ramans HarboroughCentre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Stefan KepinskiCentre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Hiroyuki KasaharaInstitute of Global Innovation Research, Tokyo University of Agriculture and Technology, Fuchu-shi, Tokyo 183-8509, Japan.
Richard NapierSchool of Life Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom.ORCID 0000-0002-0605-518X
Jiří FrimlInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.ORCID 0000-0002-8302-7596
Ken-Ichiro HayashiDepartment of Biochemistry, Okayama University of Science, Okayama 700-0005, Japan hayashi@dbc.ous.ac.jp.ORCID 0000-0002-9812-2801
Okayama University of Science · JPInstitute of Science and Technology Austria · ATNagoya University · JPUniversity of Leeds · GBUniversity of Warwick · GBRIKEN Center for Sustainable Resource Science · JP

Funding

Austrian Science Fund FWF P 29988Biotechnology and Biological Sciences Research Council BB/L009366/1
6 · The paper itself

Abstract

Polar auxin transport plays a pivotal role in plant growth and development. PIN-FORMED (PIN) auxin efflux carriers regulate directional auxin movement by establishing local auxin maxima, minima, and gradients that drive multiple developmental processes and responses to environmental signals. Auxin has been proposed to modulate its own transport by regulating subcellular PIN trafficking via processes such as clathrin-mediated PIN endocytosis and constitutive recycling. Here, we further investigated the mechanisms by which auxin affects PIN trafficking by screening auxin analogs and identified pinstatic acid (PISA) as a positive modulator of polar auxin transport in Arabidopsis (

Indexed as

EndocytosisArabidopsisArabidopsis ProteinsBiological TransportCell MembraneGravitropismHypocotylIndoleacetic AcidsPhenotypePhenylacetatesPlant RootsPlant ShootsSignal TransductionArabidopsis ProteinsIndoleacetic AcidsPhenylacetatesphenylacetic acidpinstatic acid

Identifiers

PMID30936248
PMCPMC6548234
OpenAlexW2931173915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.