Evidence map›Paper›PMID 30936242›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Circuits That Mediate Expression of Signaled Active Avoidance Converge in the Pedunculopontine Tegmentum.

Sebastian Hormigo, German Vega-Flores, Victor Rovira, Manuel A Castro-Alamancos

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  12. The Orienting Reflex Reveals Behavioral States Set by Demanding Contexts: Role of the Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  13. Caution Influences Avoidance and Approach Behaviors Differently.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  14. A Signaled Locomotor Avoidance Action Is Fully Represented in the Neural Activity of the Midbrain Tegmentum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  15. Basal Ganglia Output Has a Permissive Non-Driving Role in a Signaled Locomotor Action Mediated by the Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sebastian HormigoDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129.
German Vega-FloresDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129.
Victor RoviraDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129.
Manuel A Castro-AlamancosDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129 castrolab@outlook.com.ORCID 0000-0002-2916-9585
Drexel University · US

Funding

Sensory pathways for stimulus detection during behaviorR35NS097272 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CASTRO-ALAMANCOS, MANUEL A · 2017 to 2024
$4.3M
Neural mechanisms of active avoidance behaviorR01NS104810 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CASTRO-ALAMANCOS, MANUEL A · 2018 to 2022
$2.8M
NINDS NIH HHS R01 NS104810NINDS NIH HHS R35 NS097272
6 · The paper itself

Abstract

An innocuous sensory stimulus that reliably signals an upcoming aversive event can be conditioned to elicit locomotion to a safe location before the aversive outcome ensues. The neural circuits that mediate the expression of this signaled locomotor action, known as

Indexed as

AnimalsAvoidance LearningBrain MappingCarrier ProteinsClozapineConditioning, ClassicalDependovirusDrinking BehaviorElectroshockEscape ReactionGABAergic NeuronsGain of Function MutationGenes, ReporterGenetic VectorsLightMiceCarrier Proteinschannelopsin-2, Chlamydomonas reinhardtiiClozapineclozapine N-oxideReceptors, G-Protein-CoupledRecombinant Fusion Proteins

Identifiers

PMID30936242
PMCPMC6554632
OpenAlexW2934873624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.