Evidence map›Paper›PMID 30936204›Full record

ArticleThe Journal of biological chemistry2019

The unique trimeric assembly of the virulence factor HtrA from

Zhemin Zhang, Qi Huang, Xuan Tao, Guobing Song, Peng Zheng, Hongyan Li, Hongzhe Sun, Wei Xia

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zhemin ZhangMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.
Qi HuangMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.
Xuan TaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.
Guobing SongState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Peng ZhengState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Hongyan LiDepartment of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.
Hongzhe SunDepartment of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.
Wei XiaMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: xiawei5@mail.sysu.edu.cn.
Sun Yat-sen University · CNNanjing University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge of the molecular mechanisms of specific bacterial virulence factors can significantly contribute to antibacterial drug discovery.

Indexed as

Models, BiologicalAntigens, CDBacterial ProteinsCadherinsCrystallography, X-RayHelicobacter pyloriHumansProtein DomainsSerine EndopeptidasesSubstrate SpecificityVirulence FactorsAntigens, CDBacterial ProteinsCadherinsCDH1 protein, humanSerine EndopeptidasesVirulence FactorsHelicobacter pylorihigh-temperature requirement A (HtrA)PDZ domainprotein structuresecretionserine proteasevirulence factor

Identifiers

PMID30936204
PMCPMC6527169
OpenAlexW2925556450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.