Evidence map›Paper›PMID 30936203›Full record

ArticleThe Journal of biological chemistry2019

Heterologous regulation of CXCR4 lysosomal trafficking.

Adriana Caballero, Sarah A Mahn, Mudassir S Ali, M Rose Rogers, Adriano Marchese

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Natural lung-tropic TJournal for immunotherapy of cancer · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. CREB1-driven CXCR4Nature communications · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Adriana CaballeroDepartment of Pharmacology, Loyola University Chicago, Maywood, Illinois 60153.
Sarah A MahnDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Mudassir S AliDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
M Rose RogersDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Adriano MarcheseDepartment of Pharmacology, Loyola University Chicago, Maywood, Illinois 60153; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226. Electronic address: amarchese@mcw.edu.
Medical College of Wisconsin · USLoyola University Chicago · USLoyola University Medical Center · US

Funding

Role of beta-arrestins in G protein-coupled receptor sorting and signalingR01GM106727 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2014 to 2022
$2.9M
GPCR regulation of Akt signalingR01GM122889 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI MARCHESE, ADRIANO · 2017 to 2020
$1.3M
NIGMS NIH HHS R01 GM106727NIGMS NIH HHS R01 GM122889
6 · The paper itself

Abstract

G protein-coupled receptor (GPCR) signaling is regulated by members of the protein kinase C (PKC) and GPCR kinase (GRK) families, although the relative contribution of each to GPCR function varies among specific GPCRs. The C

Indexed as

ProteolysisSignal TransductionUbiquitinationChemokine CXCL12Chemokine CXCL13Enzyme ActivationG-Protein-Coupled Receptor KinasesHEK293 CellsHeLa CellsHumansLysosomesProtein Kinase CProtein TransportReceptors, CXCR4Repressor ProteinsTetradecanoylphorbol AcetateChemokine CXCL12Chemokine CXCL13CXCL12 protein, humanCXCL13 protein, humanCXCR4 protein, humanG-protein-coupled receptor kinase 6G-Protein-Coupled Receptor KinasesITCH protein, humanProtein Kinase CReceptors, CXCR4Repressor ProteinsTetradecanoylphorbol AcetateUbiquitin-Protein LigaseschemokineCXC chemokine receptor type 4 (CXCR4)cyclic AMP (cAMP)G protein-coupled receptor (GPCR)heterotrimeric G proteinlysosomal traffickingphorbol esterprotein kinase C (PKC)receptor degradationreceptor desensitizationreceptor down-regulationreceptor endocytosisreceptor internalizationreceptor modificationreceptor protein serine/threonine kinasesignal transduction

Identifiers

PMID30936203
PMCPMC6527173
OpenAlexW2933822537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.