Evidence map›Paper›PMID 30936199›Full record

ArticleCold Spring Harbor molecular case studies2019

Identification of a secondary

Danielle M Pendrick, Jennifer A Oberg, Susan J Hsiao, Wendy K Chung, Carrie Koval, Anthony Sireci, Jennifer H Kuo, Prakash Satwani, Chana L Glasser, Maria Luisa Sulis and 2 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. A systematic literature review of disclosure practices and reported outcomes for medically actionable genomic secondary findings.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Danielle M Pendrick *Department of Pathology and Cell Biology, New York, New York 10032, USA.ORCID 0000-0003-2723-0319
Jennifer A Oberg *Department of Pediatrics, New York, New York 10032, USA.ORCID 0000-0002-9135-3391
Susan J HsiaoDepartment of Pathology and Cell Biology, New York, New York 10032, USA.ORCID 0000-0002-0319-4969
Wendy K ChungDepartment of Pediatrics, New York, New York 10032, USA.ORCID 0000-0003-3438-5685
Carrie KovalNew York Presbyterian Hospital, New York, New York 10032, USA.
Anthony SireciDepartment of Pathology and Cell Biology, New York, New York 10032, USA.
Jennifer H KuoDepartment of Surgery, Columbia University Medical Center, New York, New York 10032, USA.ORCID 0000-0001-5078-7882
Prakash SatwaniDepartment of Pediatrics, New York, New York 10032, USA.ORCID 0000-0003-3867-9066
Chana L GlasserDivision of Pediatric Hematology/Oncology, NYU-Winthrop Hospital, Mineola, New York 11501, USA.
Maria Luisa SulisDepartment of Pathology and Cell Biology, New York, New York 10032, USA.ORCID 0000-0003-2110-0193
Mahesh M MansukhaniDepartment of Pathology and Cell Biology, New York, New York 10032, USA.ORCID 0000-0003-2044-0751
Julia L Glade BenderDepartment of Pediatrics, New York, New York 10032, USA.ORCID 0000-0001-5316-6440
New York Stem Cell Foundation · USMemorial Sloan Kettering Cancer Center · USNew York University · USColumbia University Irving Medical Center · USNew Mexico Cancer Center · USNewYork–Presbyterian Hospital · USWinthrop-University Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The incorporation of tumor-normal genomic testing into oncology can identify somatic mutations that inform therapeutic measures but also germline variants associated with unsuspected cancer predisposition. We describe a case in which a

Indexed as

Germ-Line MutationCarcinoma, NeuroendocrineChild, PreschoolFathersHumansIncidental FindingsLeukemia, Myeloid, AcuteMaleNeoplasm MetastasisNeoplasm Recurrence, LocalPedigreeProto-Oncogene Proteins c-retSequence Analysis, DNAThyroid NeoplasmsProto-Oncogene Proteins c-retRET protein, humanacute myeloid leukemiamedullary thyroid carcinoma

Identifiers

PMID30936199
PMCPMC6549565
OpenAlexW2933937654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.