Evidence map›Paper›PMID 30936165›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2019

Risk of severe maternal morbidity associated with cesarean delivery and the role of maternal age: a population-based propensity score analysis.

Diane Korb, François Goffinet, Aurélien Seco, Sylvie Chevret, Catherine Deneux-Tharaux, EPIMOMS Study Group

Abstract read
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Transvaginal hemiperitoneal cervical cerclage for cervical insufficiency: A single-center retrospective study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  7. Article
  8. The association of NICU capacity strain with neonatal mortality and morbidity.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Cesarean Delivery Outcomes for Patients with Coronavirus Disease-2019 in the USA.Journal of racial and ethnic health disparities · 2025
    Article
  14. Review
  15. Article
  16. The impact of volume and neonatal level of care on outcomes of moderate and late preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Diane KorbINSERM U1153 (Korb, Goffinet, Seco, Deneux-Tharaux), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Research Center for Epidemiology and Biostatistics Sorbonne Paris Cité (CRESS), Paris Descartes University; Department of Obstetrics and Gynecology (Korb), Robert Debré Hospital, l'Assistance publique - hôpitaux de Paris (APHP); Port-Royal Maternity Unit (Goffinet), Cochin Hospital, APHP; Clinical Research Unit of Paris Descartes Necker Cochin (Seco), APHP; Biostatistics and Clinical Epidemiology (Chevret), ECSTRA Team, INSERM, Paris Diderot Sorbonne University, Paris, France diane.korb@inserm.fr.
François GoffinetINSERM U1153 (Korb, Goffinet, Seco, Deneux-Tharaux), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Research Center for Epidemiology and Biostatistics Sorbonne Paris Cité (CRESS), Paris Descartes University; Department of Obstetrics and Gynecology (Korb), Robert Debré Hospital, l'Assistance publique - hôpitaux de Paris (APHP); Port-Royal Maternity Unit (Goffinet), Cochin Hospital, APHP; Clinical Research Unit of Paris Descartes Necker Cochin (Seco), APHP; Biostatistics and Clinical Epidemiology (Chevret), ECSTRA Team, INSERM, Paris Diderot Sorbonne University, Paris, France.
Aurélien SecoINSERM U1153 (Korb, Goffinet, Seco, Deneux-Tharaux), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Research Center for Epidemiology and Biostatistics Sorbonne Paris Cité (CRESS), Paris Descartes University; Department of Obstetrics and Gynecology (Korb), Robert Debré Hospital, l'Assistance publique - hôpitaux de Paris (APHP); Port-Royal Maternity Unit (Goffinet), Cochin Hospital, APHP; Clinical Research Unit of Paris Descartes Necker Cochin (Seco), APHP; Biostatistics and Clinical Epidemiology (Chevret), ECSTRA Team, INSERM, Paris Diderot Sorbonne University, Paris, France.
Sylvie ChevretINSERM U1153 (Korb, Goffinet, Seco, Deneux-Tharaux), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Research Center for Epidemiology and Biostatistics Sorbonne Paris Cité (CRESS), Paris Descartes University; Department of Obstetrics and Gynecology (Korb), Robert Debré Hospital, l'Assistance publique - hôpitaux de Paris (APHP); Port-Royal Maternity Unit (Goffinet), Cochin Hospital, APHP; Clinical Research Unit of Paris Descartes Necker Cochin (Seco), APHP; Biostatistics and Clinical Epidemiology (Chevret), ECSTRA Team, INSERM, Paris Diderot Sorbonne University, Paris, France.
Catherine Deneux-TharauxINSERM U1153 (Korb, Goffinet, Seco, Deneux-Tharaux), Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Research Center for Epidemiology and Biostatistics Sorbonne Paris Cité (CRESS), Paris Descartes University; Department of Obstetrics and Gynecology (Korb), Robert Debré Hospital, l'Assistance publique - hôpitaux de Paris (APHP); Port-Royal Maternity Unit (Goffinet), Cochin Hospital, APHP; Clinical Research Unit of Paris Descartes Necker Cochin (Seco), APHP; Biostatistics and Clinical Epidemiology (Chevret), ECSTRA Team, INSERM, Paris Diderot Sorbonne University, Paris, France.
EPIMOMS Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShort-term maternal complications of cesarean delivery remain uncertain because of confounding by indication. Our objective was to assess whether cesarean delivery is associated with severe acute intra- or postpartum maternal morbidity compared with vaginal delivery, overall and according to the timing of the cesarean.

methodsWe performed a case-control analysis using data from EPIMOMS, a prospective population-based study of deliveries at 22 gestation weeks or later from 6 regions of France in 2012-2013. Cases of intra- or postpartum severe acute maternal morbidity that were not a result of a condition present before delivery were compared with controls randomly selected in a 1/50 ratio. Associations between delivery modes and severe acute maternal morbidity were estimated in a propensity score-matched sample.

resultsAmong 182 300 deliveries, we identified 1444 cases and 3464 controls. The proportion of cesarean delivery was significantly higher among cases than controls (36.0% v. 18.2%). In the propensity score-matched analysis, cesarean deliveries were significantly associated with a higher risk of severe acute maternal morbidity (adjusted odds ratio [OR] 1.8, 95% confidence interval [CI] 1.5-2.2). This association increased with maternal age and was particularly marked for women aged 35 years or older (adjusted OR 2.9, 95% CI 1.9-4.4). This increased risk was significant for cesarean deliveries during labour in women of all age groups and for those before labour only in women aged 35 years or older (adjusted OR 5.1, 95% CI 2.3-11.0).

interpretationCesarean delivery is associated with a higher risk of severe acute maternal morbidity than vaginal delivery, particularly in women aged 35 years and older. Clinical decisions regarding delivery mode should account for this excess risk accordingly.

Indexed as

Maternal AgeObstetric Labor ComplicationsAdultCase-Control StudiesCesarean SectionFemaleHumansPregnancyPropensity ScoreProspective StudiesYoung Adult

Identifiers

PMID30936165
PMCPMC6443524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.