Evidence map›Paper›PMID 30935817›Full record

Observational studyThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Epidemiology and clinical characteristics of herpes zoster in a tertiary care hospital in Brazil.

Luciana Antoniolli, Camila Rodrigues, Rafael Borges, Luciano Z Goldani

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Luciana AntoniolliUniversidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Seção de Doenças Infecciosas, Porto Alegre, RS, Brazil.
Camila RodriguesUniversidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Seção de Doenças Infecciosas, Porto Alegre, RS, Brazil.
Rafael BorgesUniversidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Seção de Doenças Infecciosas, Porto Alegre, RS, Brazil.
Luciano Z GoldaniUniversidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Seção de Doenças Infecciosas, Porto Alegre, RS, Brazil. Electronic address: lgoldani@ufrgs.br.
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is little information on herpes zoster from hospital registries in South America. The aim of this study was to describe the epidemiological and clinical aspects of herpes zoster (HZ) in hospitalized patients.'

methodsWe searched for hospital-based records during the period from March 2000 to January 2017 in a 700-bed tertiary-care hospital located in southern Brazil. The medical records of all eligible patients were reviewed, and data regarding demographics, medical history, clinical and laboratory characteristics, treatment regimens, and clinical outcomes were collected. Patients were also evaluated for mortality.

resultsThere were 801 records of herpes zoster according to the proposed criteria. Most patients with HZ presented a cutaneous clinical form of the disease with involvement of a single dermatome (n=589, 73.5%). Additional clinical characteristics included postherpetic neuralgia (22.1%), ophthalmic HZ (7.6%) and meningoencephalitis (2.7%). Most patients presented immunocompromised conditions (64.9%) including HIV, administration of immunosuppressive agents, and malignant neoplasms. During this period, there were 105 (13.1%) deaths, which were mostly unrelated to HZ. Five deaths were related to HZ meningoencephalitis.

conclusionThe results of this study demonstrate a high burden of HZ disease in a Brazilian tertiary care hospital in the HZ vaccination era. Awareness of the incidence and comorbidity factors associated with HZ in Latin American countries such as Brazil contribute for adoption and implementation of strategies for immunization in this area.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionBrazilChildChild, PreschoolCross InfectionFemaleHerpes ZosterHumansInfantMaleMiddle AgedRetrospective StudiesClinical manifestationsEpidemiologyHerpes zosterTreatment

Identifiers

PMID30935817
PMCPMC9425682
OpenAlexW2933259551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.