ArticleLipids in health and disease2019
Association between lipoproteins and telomere length in US adults: data from the NHANES 1999-2002.
Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Genomic, phenomic and geographic associations of leukocyte telomere length in the United States.Nature genetics · 2026Article
- Association Between Metabolic Syndrome Components, Clinical Characteristics, and Telomere Length: Factor Analysis of Mixed Data Based Cluster Analysis of LIPIDOGEN2015 Cross-Sectional Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Association between the cholesterol, high-density lipoprotein, and glucose index and type 2 diabetes mellitus prevalence in US adults: A cross-sectional study based on National Health and Nutrition Examination Survey 2009-2018.The Journal of international medical research · 2025Article
- Joint Effects of Exercise and Ramadan Fasting on Telomere Length: Implications for Cellular Aging.Biomedicines · 2024Article
- Association between waist triglyceride index, body mass index, dietary inflammatory index, and triglyceride- glucose index with chronic kidney disease: the 1999-2018 cohort study from NHANES.Frontiers in endocrinology · 2024Article
- The association between telomere length and blood lipids: a bidirectional two-sample Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Association between Lipids, Apolipoproteins and Telomere Length: A Mendelian Randomization Study.Nutrients · 2023Article
- Investigating the impact of metabolic syndrome traits on telomere length: a Mendelian randomization study.Obesity (Silver Spring, Md.) · 2023Article
- Lipoprotein Particle Profiles Associated with Telomere Length and Telomerase Complex Components.Nutrients · 2023Article
- Fructose intake and its association with relative telomere length: an exploratory study among healthy Lebanese adults.Frontiers in nutrition · 2023Article
- The Length of Leukocyte and Femoral Artery Telomeres in Patients with Peripheral Atherosclerosis.Genes · 2022Article
- Cardiometabolic profile and leukocyte telomere length in a Black South African population.Scientific reports · 2022Article
- Telomere Length and Oxidative Stress and Its Relation with Metabolic Syndrome Components in the Aging.Biology · 2021Review
- Preoperative Creatinine Clearance and Mortality of Elective Cardiac Surgery in Hospitalization: A Secondary Analysis.Frontiers in cardiovascular medicine · 2021Article
- Association of leukocyte telomere length with metabolic syndrome in type 2 diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Telomere Length Changes in Children With Cushing Disease: A Pilot Study.Journal of the Endocrine Society · 2020Article
- Association of Lactate Dehydrogenase with In-Hospital Mortality in Patients with Acute Aortic Dissection: A Retrospective Observational Study.International journal of hypertension · 2020Article
- The relationship between cholesterol, high-density lipoprotein, and glucose index and hypertension: A study based on two national cohorts.Science progressArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence regarding the correlation between lipoproteins and telomere length in US adults is limited. We aimed to investigate whether lipoproteins was associated with telomere length using US National Health and Nutrition Examination Survey (NHANES) database.
methodsA total of 6468 selected participants were identified in the NHANES Data Base (1999-2002). The independent and dependent variables were lipoproteins and telomere length, respectively. The covariates included demographic data, dietary data, physical examination data, and comorbidities.
resultsIn fully-adjusted model, we found that 0.1 differences of telomere length were positively associated with HDL-C [0.19 (95% CI 0.07, 0.31)], while the associations between LDL-C [0.19 (95% CI -0.27, 0.65)], TG [- 1.00 (95% CI -2.09, 0.07) and telomere length were not detected. By nonlinearity test, only the relationship between HDL-C and telomere length was nonlinear. The inflection point we got was 1.25. On the left side of the inflection point (telomere length ≤ 1.25), a difference in 0.1 of telomere length was associated with 0.50 difference in HDL-C.
conclusionAfter adjusting for demographic data, dietary data, physical examination data, and comorbidities, telomere length is not associated with LDL-C and TG, but is positively associated with HDL-C when telomere length is less than 1.25.
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