ArticleMicrobiome2019
W
Article in Microbiome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Anti-osteoporotic drugs affect the pathogenesis of gut microbiota and its metabolites: a clinical study.Frontiers in cellular and infection microbiology · 2023Trial
- Early Apple Bruise Detection via Discrete Hyperspectral Signatures with SHAP-Guided Feature Selection and a CNN-Transformer Model.Foods (Basel, Switzerland) · 2026Article
- Weaning Influences Epithelial Morphology, Gene Expression and Gut Microbiota Composition in Piglets.Animals : an open access journal from MDPI · 2026Article
- Consumer resilience suppresses the recovery of overgrazed ecosystems.Ecological applications : a publication of the Ecological Society of America · 2026Article
- Article
- Time-series RNA metabarcoding of the activemSystems · 2025Article
- The Dominant Role of Dietary Differences in Shaping the Intestinal Microbial Communities of Grass Carp, Carp, and Crucian Carp in a Saline-Alkali Lake in Xinjiang During Winter.Microorganisms · 2025Article
- Compositional and functional gut microbiota alterations in mild cognitive impairment: links to Alzheimer's disease pathology.Alzheimer's research & therapy · 2025Article
- Effects of Therapeutic Antibiotic Exposure on the Oropharyngeal and Fecal Microbiota in Infants With Cystic Fibrosis.Pediatric pulmonology · 2025Article
- Revealing microbial community characteristics in healthy human, cat and canine salivas and looking for species-specific microbes.International journal of legal medicine · 2024Article
- Tumor-colonized Streptococcus mutans metabolically reprograms tumor microenvironment and promotes oral squamous cell carcinoma.Microbiome · 2024Article
- Adolescent alcohol use is associated with differences in the diversity and composition of the oral microbiome.Alcohol, clinical & experimental research · 2024Article
- Imprints of ecological processes in the taxonomic core community: an analysis of naturally replicated microbial communities enclosed in oil.FEMS microbiology ecology · 2024Article
- A comparison between full-length 16S rRNA Oxford nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues.Archives of microbiology · 2024Article
- Article
- Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.Molecules (Basel, Switzerland) · 2024Article
- Specialty grand challenge: how can we use integrative approaches to understand microbial community dynamics?Frontiers in systems biology · 2024Article
- Epidemiological investigation of feline chronic gingivostomatitis and its relationship with oral microbiota in Xi'an, China.Frontiers in veterinary science · 2024Article
- Antibiotic prophylaxis dysregulates dental implant placement surgery-induced osteoimmune wound healing and attenuates the alveolar bone-implant interface in mice.Journal of clinical periodontology · 2023Article
- Pollinator sharing and hybridization in a pair of dioecious figs sheds light on the pathways to speciation.Evolution letters · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundCommunity-wide analyses provide an essential means for evaluation of the effect of interventions or design variables on the composition of the microbiome. Applications of these analyses are omnipresent in microbiome literature, yet some of their statistical properties have not been tested for robustness towards common features of microbiome data. Recently, it has been reported that PERMANOVA can yield wrong results in the presence of heteroscedasticity and unbalanced sample sizes.
findingsWe develop a method for multivariate analysis of variance, [Formula: see text], based on Welch MANOVA that is robust to heteroscedasticity in the data. We do so by extending a previously reported method that does the same for two-level independent factor variables. Our approach can accommodate multi-level factors, stratification, and multiple post hoc testing scenarios. An R language implementation of the method is available at https://github.com/alekseyenko/WdStar .
conclusionOur method resolves potential for confounding of location and dispersion effects in multivariate analyses by explicitly accounting for the differences in multivariate dispersion in the data tested. The methods based on [Formula: see text] have general applicability in microbiome and other 'omics data analyses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.