Evidence map›Paper›PMID 30935114›Full record

ArticleSensors (Basel, Switzerland)2019

Ag@Au Core⁻Shell Porous Nanocages with Outstanding SERS Activity for Highly Sensitive SERS Immunoassay.

Yaqi Huang, Dajie Lin, Mengting Li, Dewu Yin, Shun Wang, Jichang Wang

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yaqi HuangCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. 16451282265@stu.wzu.edu.cn.
Dajie LinCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. lindj@wzu.edu.cn.
Mengting LiCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. 17451282201@stu.wzu.edu.cn.
Dewu YinCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. dewuyin@wzu.edu.cn.
Shun WangCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. shunwang@wzu.edu.cn.
Jichang WangCollege of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. jwang@uwindsor.ca.
Wenzhou University · CNWenzhou Medical University · CN

Funding

National Natural Science Foundation of China No.21475097 and 21471116Natural Science Foundation of Zhejiang Province LY17B050004, LY18H200025 and LY17E020003Opening Project of Zhejiang Provincial Top Key Discipline of Clinical Medicine KFJ026
6 · The paper itself

Abstract

A highly sensitive immunoassay of biomarkers has been achieved using 4-mercaptobenzoic acid-labeled Ag@Au core⁻shell porous nanocage tags and α-fetoprotein immuno-sensing chips. The Ag@Au porous nanocages were uniquely synthesized by using an Ag core as a self-sacrificial template and reducing agent, where the slow reaction process led to the formation of a porous Au layer. The size of the remaining Ag core and surface roughness of the Au shell were controlled by adjusting the chloroauric acid concentration. The porous cage exhibited excellent surface-enhanced Raman spectroscopy (SERS) activity, presumably due to a synergetic interaction between newly generated hot spots in the rough Au shell and the retained SERS activity of the Ag core. Using α-fetoprotein as a model analyte for immunoassay, the SERS signal had a wide linear range of 0.20 ng mL

Indexed as

Spectrum Analysis, Ramanalpha-FetoproteinsAntibodies, ImmobilizedGoldHumansImmunoassayLimit of DetectionNanostructuresPorositySilveralpha-FetoproteinsAntibodies, ImmobilizedGoldSilverAg core–Au shell porous nanocagesbiomarkersgalvanic replacement reactionimmunoassaysurface-enhanced Raman spectroscopy

Identifiers

PMID30935114
PMCPMC6480069
OpenAlexW2934279294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.