Evidence map›Paper›PMID 30935105›Full record

ArticleMicromachines2019

Magnetically Aligned Nanorods in Alginate Capsules (MANiACs): Soft Matter Tumbling Robots for Manipulation and Drug Delivery.

Lamar O Mair, Sagar Chowdhury, Genaro A Paredes-Juarez, Maria Guix, Chenghao Bi, Benjamin Johnson, Bradley W English, Sahar Jafari, James Baker-McKee, Jamelle Watson-Daniels and 11 more

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Alginate Sphere-Based Soft Actuators.Gels (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. In Vivo Imaging of Naked and Microencapsulated Islet Cell Transplantation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  9. Article
  10. Impact of Segmented Magnetization on the Flagellar Propulsion of Sperm-Templated Microrobots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  11. Article
  12. Review
  13. MagnetoSuture: Tetherless Manipulation of Suture Needles.IEEE transactions on medical robotics and bionics · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Lamar O MairWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. lamar.mair@gmail.com.ORCID 0000-0001-9459-3932
Sagar ChowdhuryWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. sagar353@gmail.com.ORCID 0000-0002-0296-8205
Genaro A Paredes-JuarezRussel H. Morgan Department of Radiology, Division of Magnetic Resonance Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. genaro.paredes@gmail.com.
Maria GuixMulti-Scale Robotics and Automation Lab, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. maria.guix@gmail.com.
Chenghao BiMulti-Scale Robotics and Automation Lab, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. bi10@purdue.edu.
Benjamin JohnsonMulti-Scale Robotics and Automation Lab, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. john1360@purdue.edu.
Bradley W EnglishWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. brad.w.english@gmail.com.
Sahar JafariWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. sahar.jafari2011@gmail.com.
James Baker-McKeeWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. jbakermckee@gmail.com.
Jamelle Watson-DanielsWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. jamelle.wd@gmail.com.
Olivia HaleWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. oliviahale333@gmail.com.
Pavel StepanovWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. pavstepan@gmail.com.
Danica SunWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. danica.sun5@gmail.com.
Zachary BakerWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. zgbaker54@gmail.com.
Chad RoppWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. chadropp@gmail.com.
Shailesh B RavalWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. rshailesh8504@gmail.com.ORCID 0000-0001-9202-236X
Dian R ArifinRussel H. Morgan Department of Radiology, Division of Magnetic Resonance Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. darifin@mri.jhu.edu.
Jeff W M BulteRussel H. Morgan Department of Radiology, Division of Magnetic Resonance Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. jwmbulte@mri.jhu.edu.ORCID 0000-0003-1202-1610
Irving N WeinbergWeinberg Medical Physics, Inc., North Bethesda, MD 20852, USA. inweinberg@gmail.com.
Emily E EvansDepartment of Physics, Elon University, Elon, NC 27244, USA. bevans7@elon.edu.ORCID 0000-0001-7029-0945
David J CappelleriMulti-Scale Robotics and Automation Lab, School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. dcappell@purdue.edu.ORCID 0000-0001-7222-0625
Weinberg Medical Physics (United States) · USPurdue University West Lafayette · USJohns Hopkins University · USElon University · US

Funding

Dual-mode MRI for in vivo sensing of microcapsule stability and biocompatibilityR01DK106972 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2015 to 2018
$1.7M
National Science Foundation IIP-1059286NIDDK NIH HHS R01 DK106972NIH HHS R01 DK106972NIST / US Department of Commerce 70NANB16H193
6 · The paper itself

Abstract

Soft, untethered microrobots composed of biocompatible materials for completing micromanipulation and drug delivery tasks in lab-on-a-chip and medical scenarios are currently being developed. Alginate holds significant potential in medical microrobotics due to its biocompatibility, biodegradability, and drug encapsulation capabilities. Here, we describe the synthesis of MANiACs-Magnetically Aligned Nanorods in Alginate Capsules-for use as untethered microrobotic surface tumblers, demonstrating magnetically guided lateral tumbling via rotating magnetic fields. MANiAC translation is demonstrated on tissue surfaces as well as inclined slopes. These alginate microrobots are capable of manipulating objects over millimeter-scale distances. Finally, we demonstrate payload release capabilities of MANiACs during translational tumbling motion.

Indexed as

alginate capsulesmagnetic microrobotsmagnetic nanorodsmicromanipulationrotating magnetic fieldssurface walkerstumbling robots

Identifiers

PMID30935105
PMCPMC6523834
OpenAlexW2935204786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.