Evidence map›Paper›PMID 30934989›Full record

ArticleMolecules (Basel, Switzerland)2019

A UHPLC-UV Method Development and Validation for Determining Kavalactones and Flavokavains in

Yijin Tang, Christine Fields

Open access · goldAbstract readValidation Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Chemical standardization of kava (Pharmaceutical biology · 2026
    Article
  2. Article
  3. Article
  4. A Novel Tri-Hydroxy-Methylated Chalcone Isolated fromInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yijin TangApplied Food Sciences, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA. ytang@appliedfoods.com.
Christine FieldsApplied Food Sciences, Inc., 2500 Crosspark Road, Coralville, IA 52241, USA. cfields@appliedfoods.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ultra-high-performance liquid chromatographic (UHPLC) separation was developed for six kava pyrones (methysticin, dihydromethysticin (DHM), kavain, dihydrokavain (DHK), desmethoxyyangonin (DMY), and yangonin), two unidentified components, and three Flavokavains (Flavokavain A, B, and C) in

Indexed as

Carbon DioxideChromatography, High Pressure LiquidFlavonoidsIsomerismKavaLactonesLimit of DetectionMolecular StructurePlant ExtractsPlant RootsPyransPyronesStructure-Activity RelationshipTandem Mass SpectrometryCarbon DioxideFlavonoidsLactonesmethysticinPlant ExtractsPyransPyronesflavokavainsisomerizationkavalactonesmass spectraPiper methysticum (kava)quality controlsingle-laboratory validationUHPLC-UV

Identifiers

PMID30934989
PMCPMC6479543
OpenAlexW2929086742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.