Evidence map›Paper›PMID 30934912›Full record

ArticleMarine drugs2019

Antitumoral Effect of Laurinterol on 3D Culture of Breast Cancer Explants.

Sara García-Davis, Ezequiel Viveros-Valdez, Ana R Díaz-Marrero, José J Fernández, Daniel Valencia-Mercado, Olga Esquivel-Hernández, Pilar Carranza-Rosales, Irma Edith Carranza-Torres, Nancy Elena Guzmán-Delgado

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Laurinterol, the MainMarine drugs · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara García-DavisFacultad de Ciencias Biológicas (FCB), Universidad Autónoma de Nuevo León (UANL), Av. Pedro de Alba s/n, 66450 San Nicolás de los Garza, Nuevo León, México. sara.garciadv@uanl.edu.mx.
Ezequiel Viveros-ValdezFacultad de Ciencias Biológicas (FCB), Universidad Autónoma de Nuevo León (UANL), Av. Pedro de Alba s/n, 66450 San Nicolás de los Garza, Nuevo León, México. jose.viverosvld@uanl.edu.mx.ORCID 0000-0001-5944-7972
Ana R Díaz-MarreroInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avda. Astrofísico F. Sánchez, 2, 38206 La Laguna, Tenerife, Spain. adiazmar@ull.edu.es.ORCID 0000-0002-8886-7519
José J FernándezInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avda. Astrofísico F. Sánchez, 2, 38206 La Laguna, Tenerife, Spain. jjfercas@ull.edu.es.ORCID 0000-0002-0805-8317
Daniel Valencia-MercadoServicio de Oncología Ginecológica, Unidad Médica de Alta Especialidad, Hospital de Gineco-Obstetricia No. 23, Instituto Mexicano del Seguro Social (IMSS), Avenida Constitución y Félix U. Gómez s/n, Colonia Centro, 64000 Monterrey, Nuevo León, México. davame7@hotmail.com.
Olga Esquivel-HernándezDepartamento de Anatomía Patológica, Unidad Médica de Alta Especialidad, Hospital de Gineco- Obstetricia No. 23, Instituto Mexicano del Seguro Social (IMSS), Avenida Constitución y Félix U. Gómez s/n, Colonia Centro, 64000 Monterrey, Nuevo León, México. oesh10@gmail.com.
Pilar Carranza-RosalesCentro de Investigación Biomédica del Noreste (CIBIN), Instituto Mexicano del Seguro Social (IMSS), Calle Jesús Dionisio González # 501, Col. Independencia, 64720 Monterrey, Nuevo León, México. carranza60@yahoo.com.mx.ORCID 0000-0002-8944-9298
Irma Edith Carranza-TorresFacultad de Ciencias Biológicas (FCB), Universidad Autónoma de Nuevo León (UANL), Av. Pedro de Alba s/n, 66450 San Nicolás de los Garza, Nuevo León, México. mitzba@hotmail.com.ORCID 0000-0001-8800-1443
Nancy Elena Guzmán-DelgadoDivisión de Investigación en Salud, Unidad Médica de Alta Especialidad, Hospital de Cardiología No. 34, Instituto Mexicano del Seguro Social (IMSS), Av. Lincoln S/N esquina con Enfermera María de Jesús Candia, Col. Valle Verde 2do. Sector, 64360 Monterrey, Nuevo León, México. nancyegd@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroalgae represent an important source of bioactive compounds with a wide range of biotechnological applications. Overall, the discovery of effective cytotoxic compounds with pharmaceutical potential is a significant challenge, mostly because they are scarce in nature or their total synthesis is not efficient, while the bioprospecting models currently used do not predict clinical responses. Given this context, we used three-dimensional (3D) cultures of human breast cancer explants to evaluate the antitumoral effect of laurinterol, the major compound of an ethanolic extract of

Indexed as

AnimalsAntineoplastic AgentsApoptosisBreast NeoplasmsCells, CulturedChlorocebus aethiopsFemaleHumansLaurenciaMCF-7 CellsSesquiterpenesVero CellsAntineoplastic AgentslaurinterolSesquiterpenesantitumoralbreast cancer explantsex vivoLaurencialaurinterolorganotypic culture

Identifiers

PMID30934912
PMCPMC6520734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.