Trial reportNutrients2019
Challenging the Myth of Non-Response to the Ergogenic Effects of Caffeine Ingestion on Exercise Performance.
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Pooled it
- No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.Journal of the International Society of Sports Nutrition · 2025Trial
- Efficacy of caffeine as an ergogenic aid in multiple cycling time trials.European journal of applied physiology · 2025Trial
- Can 3 mg·kgNutrients · 2021Trial
- The Performance Effect of Scheduled Carbohydrate and Caffeine Intake during Simulated Team Sport Match-Play.Nutrients · 2020Trial
- The Effects of High Doses of Caffeine on Maximal Strength and Muscular Endurance in Athletes Habituated to Caffeine.Nutrients · 2019Trial
- Review
- Exploring the potential synergistic pharmacological and psychological effects of caffeine on exercise performance: a placebo-balanced study.Biology of sport · 2026Article
- Effects of Acute Caffeine Ingestion on Physical Performance and Skill Execution in Volleyball Players: A Systematic Review and Meta-Analysis.International journal of exercise science · 2025Article
- Common questions and misconceptions about caffeine supplementation: what does the scientific evidence really show?Journal of the International Society of Sports Nutrition · 2024Review
- Effects of CurraNZ, a New Zealand Blackcurrant Extract during 1 Hour of Treadmill Running in Female and Male Marathon des Sables Athletes in Hot Conditions: Two Case Studies.Journal of functional morphology and kinesiology · 2024Article
- Brief Version of Caffeine Expectancy Questionnaire in Brazil.Frontiers in nutrition · 2021Article
- Effects ofGenes · 2020Article
- Effects of Caffeine and Coffee on Human Functioning.Nutrients · 2020Article
- Caffeine Timing Improves Lower-Body Muscular Performance: A Randomized Trial.Frontiers in nutrition · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ergogenicity of caffeine on several exercise and sport situations is well-established. However, the extent of the ergogenic response to acute caffeine ingestion might greatly vary among individuals despite using the same dosage and timing. The existence of one or several individuals that obtained minimal ergogenic effects or even slightly ergolytic effects after caffeine intake (i.e., non-responders) has been reported in several previous investigations. Nevertheless, the concept non-responding to caffeine, in terms of physical performance, relies on investigations based on the measurement of one performance variable obtained once. Recently it has been suggested that correct identification of the individual ergogenic effect induced by caffeine intake requires the repeated measurement of physical performance in identical caffeine⁻placebo comparisons. In this communication, we present data from an investigation where the ergogenic effect of acute caffeine intake (3 mg/kg) was measured eight times over a placebo in the same individuals and under the same conditions by an incremental cycling test to volitional fatigue and an adapted version of the Wingate cycling test. The ergogenic response to caffeine varied from 9% to 1% among individuals, but all participants increased both cycling power in the incremental test and Wingate mean power at least three to eight times out of eight the caffeine⁻placebo comparisons. These data expand the suggestion of a minimal occurrence of caffeine non-responders because it shows that all individuals responded to caffeine when caffeine is compared to a placebo on multiple and repeated testing sessions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.