Evidence map›Paper›PMID 30934839›Full record

ArticleInternational journal of molecular sciences2019

Modulation of Iberian Ribbed Newt Complement Component C3 by Stressors Similar to those Encountered during a Stay Onboard the International Space Station.

Nathan Guéguinou, Jérémy Jeandel, Sandra Kaminski, Sarah Baatout, Stéphanie Ghislin, Jean-Pol Frippiat

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nathan GuéguinouStress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de Lorraine, 9 avenue de la Foret de Haye, F-54500 Vandœuvre-lès-Nancy, France. nathan.gueguinou@laposte.net.
Jérémy JeandelStress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de Lorraine, 9 avenue de la Foret de Haye, F-54500 Vandœuvre-lès-Nancy, France. jeremy.jeandel@univ-lorraine.fr.
Sandra KaminskiStress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de Lorraine, 9 avenue de la Foret de Haye, F-54500 Vandœuvre-lès-Nancy, France. sandra.kaminski@univ-lorraine.fr.
Sarah BaatoutRadiobiology Unit, SCK·CEN, Boeretang 200, B-2400 Mol, Belgium. sarah.baatout@sckcen.be.
Stéphanie GhislinStress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de Lorraine, 9 avenue de la Foret de Haye, F-54500 Vandœuvre-lès-Nancy, France. stephanie.ghislin@univ-lorraine.fr.
Jean-Pol FrippiatStress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de Lorraine, 9 avenue de la Foret de Haye, F-54500 Vandœuvre-lès-Nancy, France. jean-pol.frippiat@univ-lorraine.fr.ORCID 0000-0002-4027-6269
Stress, immunité, pathogènesBelgian Nuclear Research Centre · BE

Funding

Belgian Science Policy 42-000-90-380, C4000109861 ESA/PRODEX IMPULSE contractCentre National d'Etudes Spatiales DAR 4800000786, DAR 4800000841 & DAR 4800000894
6 · The paper itself

Abstract

The complement system plays an important role in inflammation, innate and acquired immunity, as well as homeostasis. Despite these functions, the effects of spaceflight conditions on the complement system have not yet been intensively studied. Consequently, we investigated the effects of five types of chronic stressors, similar to those encountered during a stay onboard the International Space Station, on C3 expression in larvae of the urodele amphibian

Indexed as

Space FlightStress, PhysiologicalAnimalsCircadian RhythmComplement C3DarknessDisease Models, AnimalHindlimb SuspensionMiceSalamandridaeTranscription, GeneticVibrationWeightlessness SimulationComplement C3amphibiangravityimmunityinflammationspaceflight

Identifiers

PMID30934839
PMCPMC6479312
OpenAlexW2924216098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.