Evidence map›Paper›PMID 30934838›Full record

ArticleInternational journal of molecular sciences2019

The Interplay between miRNA-Related Variants and Age-Related Macular Degeneration: EVIDENCE of Association of

Claudia Strafella, Valeria Errichiello, Valerio Caputo, Gianluca Aloe, Federico Ricci, Andrea Cusumano, Giuseppe Novelli, Emiliano Giardina, Raffaella Cascella

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. RNA therapeutics for retinal diseases.Expert opinion on biological therapy · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. RNAseq-Based Prioritization RevealedInternational journal of molecular sciences · 2020
    Article
  13. Article
  14. Article
  15. Expression of VEGFA-regulating miRNAs and mortality in wet AMD.Journal of cellular and molecular medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia StrafellaMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, 00142 Rome, Italy. claudia.strafella@gmail.com.
Valeria ErrichielloMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, 00142 Rome, Italy. valeriaerrichiello@hotmail.it.
Valerio CaputoMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, 00142 Rome, Italy. v.caputo91@gmail.com.
Gianluca AloeUOSD Retinal Pathology PTV Foundation Policlinico Tor Vergata University, 00133 Rome, Italy. gianluca.aloe@alice.it.
Federico RicciUOSD Retinal Pathology PTV Foundation Policlinico Tor Vergata University, 00133 Rome, Italy. rccfrc00@gmail.com.
Andrea CusumanoUOSD Retinal Pathology PTV Foundation Policlinico Tor Vergata University, 00133 Rome, Italy. cusumano@tin.it.
Giuseppe NovelliDepartment of Biomedicine and Prevention, Tor Vergata University, 00133 Rome, Italy. novelli@med.uniroma2.it.
Emiliano GiardinaMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, 00142 Rome, Italy. emiliano.giardina@uniroma2.it.
Raffaella CascellaMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, 00142 Rome, Italy. raffaellacascella@virgilio.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex interplay among genetic, epigenetic, and environmental variables is the basis for the multifactorial origin of age-related macular degeneration (AMD). Previous results highlighted that single nucleotide polymorphisms (SNPs) of

Indexed as

Genetic Predisposition to DiseaseAgedAllelesFemaleHumansMacular DegenerationMaleMicroRNAsNucleic Acid ConformationPolymorphism, Single NucleotideRisk FactorsMicroRNAsMIRN146 microRNA, humanMIRN27 microRNA, humanAMDchoroidal neovascularizationepigeneticsinflammationmiRNAsneurodegenerationsusceptibility

Identifiers

PMID30934838
PMCPMC6480223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.