Evidence map›Paper›PMID 30934825›Full record

ReviewInternational journal of molecular sciences2019

Spare Parts from Discarded Materials: Fetal Annexes in Regenerative Medicine.

Giulia Gaggi, Pascal Izzicupo, Andrea Di Credico, Silvia Sancilio, Angela Di Baldassarre, Barbara Ghinassi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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  11. Review
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  14. Article
  15. Strategic Tools in Regenerative and Translational Dentistry.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giulia GaggiDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. giulia.gaggi@unich.it.
Pascal IzzicupoDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. izzicupo@unich.it.ORCID 0000-0001-6944-8995
Andrea Di CredicoDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. andrea.dicredico@hotmail.it.
Silvia SancilioDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. silvia.sancilio@unich.it.
Angela Di BaldassarreDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. angela.dibaldassarre@unich.it.ORCID 0000-0002-4473-4909
Barbara GhinassiDepartment of Medicine and Aging Sciences, University "G. D'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy. b.ghinassi@unich.it.ORCID 0000-0002-3529-2790

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca SIR2014-RBSI140GLQ.
6 · The paper itself

Abstract

One of the main aims in regenerative medicine is to find stem cells that are easy to obtain and are safe and efficient in either an autologous or allogenic host when transplanted. This review provides an overview of the potential use of the fetal annexes in regenerative medicine: we described the formation of the annexes, their immunological features, the new advances in the phenotypical characterization of fetal annexes-derived stem cells, the progressions obtained in the analysis of both their differentiative potential and their secretoma, and finally, the potential use of decellularized fetal membranes. Normally discarded as medical waste, the umbilical cord and perinatal tissue not only represent a rich source of stem cells but can also be used as a scaffold for regenerative medicine, providing a suitable environment for the growth and differentiation of stem cells.

Indexed as

Regenerative MedicineCell DifferentiationFetusHumansParacrine CommunicationStem CellsWharton Jellyamniotic epithelial cellsamniotic fluid stem cellsamniotic mesenchymal cellschorionic mesenchymal stromal cellsdecellularized tissuesdifferentiationfetal membranesperinatal stem cellsregenerative medicineWharton’s jelly stem cells

Identifiers

PMID30934825
PMCPMC6479500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.