ArticleInternational journal of molecular sciences2019
Chondrocyte Culture Parameters for Matrix-Assisted Autologous Chondrocyte Implantation Affect Catabolism and Inflammation in a Rabbit Model.
Martin Sauerschnig, Markus T Berninger, Theresa Kaltenhauser, Michael Plecko, Gabriele Wexel, Martin Schönfelder, Valerie Wienerroither, Andreas B Imhoff, Philip B Schöttle, Elizabeth Rosado Balmayor and 1 more
Open access · goldAbstract read
In one paragraphArticle in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors at 4 institutions in 3 countries.
Martin SauerschnigDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. martin.sauerschnig@auva.at.ORCID 0000-0003-0690-2892 Markus T BerningerDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. markus.berninger@gmx.at.
Theresa KaltenhauserDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. theresa@suetfels.com.
Michael PleckoTrauma Hospital Graz, Unfallkrankenhaus der Allgemeinen Unfallversicherungsanstalt (AUVA), Teaching Hospital Medical University Graz, Graz 8010, Austria. michael.plecko@auva.at.
Gabriele WexelDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. the.rabbithunter@gmx.de.
Martin SchönfelderExercise Biology, Technical University of Munich, 80809 Munich, Germany. martin.schoenfelder@tum.de.ORCID 0000-0002-3003-3378 Valerie WienerroitherTrauma Hospital Graz, Unfallkrankenhaus der Allgemeinen Unfallversicherungsanstalt (AUVA), Teaching Hospital Medical University Graz, Graz 8010, Austria. valerie.wienerroither@medunigraz.at.
Andreas B ImhoffDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. a.imhoff@sportortho.de.
Philip B SchöttleDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. p_schoettle@web.de.
Elizabeth Rosado BalmayorExperimental Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. elizabeth.rosado-balmayor@tum.de.ORCID 0000-0002-0484-4847 Gian M SalzmannDepartment of Orthopedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. gian.salzmann@kws.ch.
TUM Klinikum · DEAllgemeine Unfallversicherungsanstalt · ATMedical University of Graz · ATTechnical University of Munich · DE
Funding
Gesellschaft für Arthroskopie und Gelenkchirurgie (AGA) 26/2007
6 · The paper itselfAbstract
Cartilage defects represent an increasing pathology among active individuals that affects the ability to contribute to sports and daily life. Cell therapy, such as autologous chondrocyte implantation (ACI), is a widespread option to treat larger cartilage defects still lacking standardization of in vitro cell culture parameters. We hypothesize that mRNA expression of cytokines and proteases before and after ACI is influenced by in vitro parameters: cell-passage, cell-density and membrane-holding time. Knee joint articular chondrocytes, harvested from rabbits (
Indexed as
AnimalsCells, CulturedChondrocytesCytokinesDisease Models, AnimalExtracellular MatrixInflammationInflammation MediatorsMatrix MetalloproteinasesRabbitsRNA, MessengerTransplantation, AutologousCytokinesInflammation MediatorsMatrix MetalloproteinasesRNA, Messengeranimal modelcell densitycell passagecytokinesmatrix-assisted autologous chondrocyte implantationmatrix metalloproteinasesmembrane-holding time
Identifiers
PMID30934789
PMCPMC6479589
OpenAlexW2925307549
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390