Evidence map›Paper›PMID 30934681›Full record

ArticleMolecules (Basel, Switzerland)2019

A Single Mutation Increases the Thermostability and Activity of

Wan-Li Zhu, Sheng Hu, Chang-Jiang Lv, Wei-Rui Zhao, Hong-Peng Wang, Jia-Qi Mei, Le-He Mei, Jun Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Engineering Novel (Applied and environmental microbiology · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wan-Li ZhuCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China. urnotzhuwanli@163.com.
Sheng HuDepartment of Biological and Pharmaceutical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China. genegun@zju.edu.cn.
Chang-Jiang LvSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China. yangtzelv@zju.edu.cn.
Wei-Rui ZhaoDepartment of Biological and Pharmaceutical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China. zwr166@sohu.com.
Hong-Peng WangSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China. wanghongpeng@hotmail.com.
Jia-Qi MeiDepartment of Chemical Engineering, University of Utah, Salt Lake City, UT 84102, USA. meijiaqi123@gmail.com.
Le-He MeiDepartment of Biological and Pharmaceutical Engineering, Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China. meilh@zju.edu.cn.
Jun HuangSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China. huangjun@zust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhancing the thermostability of (

Indexed as

MutationAminesAspergillusEnzyme StabilityKineticsMolecular ConformationMutagenesis, Site-DirectedStructure-Activity RelationshipThermodynamicsTransaminasesAminesTransaminasesamine transaminasedifferential scanning fluorimetry (DSF)mutual information (MI)saturation mutagenesisthermostability

Identifiers

PMID30934681
PMCPMC6479498

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.