Evidence map›Paper›PMID 30934664›Full record

ArticleMolecules (Basel, Switzerland)2019

The Effect of Rhodamine-Derived Superparamagnetic Maghemite Nanoparticles on the Motility of Human Mesenchymal Stem Cells and Mouse Embryonic Fibroblast Cells.

Larisa Baiazitova, Josef Skopalik, Jiri Chmelik, Inna Zumberg, Vratislav Cmiel, Katerina Polakova, Ivo Provaznik

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. RSC advances · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Larisa BaiazitovaDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. xbaiaz00@stud.feec.vutbr.cz.ORCID 0000-0002-3178-4202
Josef SkopalikDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. skopalik@feec.vutbr.cz.
Jiri ChmelikDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. chmelikj@feec.vutbr.cz.ORCID 0000-0001-9950-6279
Inna ZumbergDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. xzumbe00@stud.feec.vutbr.cz.
Vratislav CmielDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. cmiel@feec.vutbr.cz.
Katerina PolakovaRegional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, 17 listopadu 12, 771 46 Olomouc, Czech Republic. dr.kacka.polakova@gmail.com.
Ivo ProvaznikDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 3082/12, 61600 Brno, Czech Republic. provaznik@feec.vutbr.cz.ORCID 0000-0002-3422-7938

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles have become popular in life sciences in the last few years. They have been produced in many variants and have recently been used in both biological experiments and in clinical applications. Due to concerns over nanomaterial risks, there has been a dramatic increase in investigations focused on safety research. The aim of this paper is to present the advanced testing of rhodamine-derived superparamagnetic maghemite nanoparticles (SAMN-R), which are used for their nontoxicity, biocompatibility, biodegradability, and magnetic properties. Recent results were expanded upon from the basic cytotoxic tests to evaluate cell proliferation and migration potential. Two cell types were used for the cell proliferation and tracking study: mouse embryonic fibroblast cells (3T3) and human mesenchymal stem cells (hMSCs). Advanced microscopic methods allowed for the precise quantification of the function of both cell types. This study has demonstrated that a dose of nanoparticles lower than 20 µg·cm

Indexed as

Magnetite NanoparticlesAnimalsBiomarkersCell LineCell MovementCell ProliferationFibroblastsFlow CytometryHumansImmunophenotypingMesenchymal Stem CellsMiceReactive Oxygen SpeciesRhodaminesBiomarkersMagnetite NanoparticlesReactive Oxygen SpeciesRhodaminescytotoxicityfibroblast cellsmagnetic nanoparticlesmesenchymal stem cellssingle-cell migrationwound healing assay

Identifiers

PMID30934664
PMCPMC6479307

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.