ArticleInternational journal of environmental research and public health2019
Impact of Gender and Age on Rapid Eye Movement-Related Obstructive Sleep Apnea: A Clinical Study of 3234 Japanese OSA Patients.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 40 citations in OpenAlex.
- The efficacy of a titrated tongue-stabilizing device on obstructive sleep apnea: a quasi-experimental study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Trial
- Advances in the Diagnosis and Treatment of Obstructive Sleep Apnea in Women.Pulmonary therapy · 2026Review
- Obstructive Sleep Apnea Syndrome in women: gender in sleep respiratory medicine is a first step towards personalized medicine.Sleep & breathing = Schlaf & Atmung · 2025Review
- Rapid eye movement dependency is associated with increased inflammatory activity in obstructive sleep apnea syndrome.Brain and behavior · 2024Article
- REM sleep obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Association between Rapid Eye Movement Obstructive Sleep Apnea and Metabolic Syndrome in a Japanese Population.Internal medicine (Tokyo, Japan) · 2023Article
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Association of obstructive sleep apnoea with cardiovascular events in women and men with acute coronary syndrome.The European respiratory journal · 2023Article
- A Narrative Review of Sex and Gender Differences in Sleep Disordered Breathing: Gaps and Opportunities.Life (Basel, Switzerland) · 2022Review
- Subtypes of obstructive sleep apnea in children and related factors.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Long-term outcomes regarding arterial stiffness and carotid artery atherosclerosis in female patients with rapid eye movement obstructive sleep apnea.The Journal of international medical research · 2022Article
- [A case of REM obstructive sleep apnea with nocturnal panic-like episode as the main symptom].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022Article
- Estimated respiratory arousal threshold in patients with rapid eye movement obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2022Observational
- Nocturnal Blood Pressure Fluctuations in Patients with Rapid Eye Movement-Related Obstructive Sleep Apnea.Journal of clinical medicine · 2021Article
- Obstructive sleep apnea and respiratory center regulation abnormality.Sleep & breathing = Schlaf & Atmung · 2021Review
- Sex differences in the association between arterial hypertension, blood pressure, and sleep apnea in the general population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- [Clinical characteristics of obstructive sleep apnea hypopnea syndrome in different genders].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- Article
- Association between Obstructive Sleep Apnea and Type 2 Diabetes Mellitus: A Dose-Response Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Treatment outcome of oral appliance in patients with REM-related obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2020Observational
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid eye movement (REM)-related obstructive sleep apnea (OSA) is characterized by apnea and hypopnea events due to airway collapse occurring predominantly or exclusively during REM sleep. Previous studies have reported that REM-related OSA occurs more commonly in women and younger individuals. However, external validity of this tendency has not been confirmed in a large clinical sample. The objective of this study was to evaluate the effect of gender and age on REM-related OSA after adjustment for several covariates based on their established clinical relationships to gender difference in OSA. A total of 3234 Japanese patients with OSA were enrolled in this study. We confirmed that female sex is an important risk factor for REM-related OSA, as reported by previous studies. Moreover, we showed that women aged over 50 years were at a greater risk than those aged under 50 years. These results suggest that hormonal changes in women might play an important role in REM-related OSA and might reflect its unknown pathophysiological characteristics.
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