Evidence map›Paper›PMID 30934553›Full record

ArticleMaterials (Basel, Switzerland)2019

Influence of the Elastic Modulus on the Osseointegration of Dental Implants.

Aritza Brizuela, Mariano Herrero-Climent, Elisa Rios-Carrasco, Jose Vicente Rios-Santos, Roman A Pérez, Jose Maria Manero, Javier Gil Mur

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 105 citations in OpenAlex.

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  11. Anisotropy of Additively Manufactured Metallic Materials.Materials (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Aritza BrizuelaDepartment of Prosthodontics and Occlusion, School of Dentistry, University of Oviedo, 37006 Oviedo, Spain. aritzabrizuela@hotmail.com.
Mariano Herrero-ClimentFaculty of Odontology, University of Seville, 41009 Seville, Spain. mariano@herrerocliment.com.
Elisa Rios-CarrascoFaculty of Odontology, University of Seville, 41009 Seville, Spain. elisarioscarrasco@gmail.com.
Jose Vicente Rios-SantosFaculty of Odontology, University of Seville, 41009 Seville, Spain. jvrios@us.es.ORCID 0000-0002-8121-6166
Roman A PérezInstitute of Bioengineering, School of Dentistry, Universitat Internacional de Catalunya, 08195 Barcelona, Spain. rperezan@uic.es.ORCID 0000-0002-0823-2303
Jose Maria ManeroBiomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgy, Technical University of Catalonia (UPC), EEBE, 08019 Barcelona, Spain. jose.maria.manero@upc.edu.
Javier Gil MurInstitute of Bioengineering, School of Dentistry, Universitat Internacional de Catalunya, 08195 Barcelona, Spain. xavier.gil@uic.cat.
Universidad de Sevilla · ESUniversitat Internacional de Catalunya · ESUniversidad de Oviedo · ESUniversitat Politècnica de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The load transfer from metallic prosthesis to tissue plays an important role in the success of a designed device. From a mechanical behavior point of view, the load transfer will be favored when the elastic modulus between the metallic implant and the bone tissue are similar. Titanium and Ti-6Al-4V are the most commonly used metals and alloys in the field of dental implants, although they present high elastic moduli and hence trigger bone resorption. We propose the use of low-modulus β-type titanium alloys that can improve the growth of new bone surrounding the implant. We designed dental implants with identical morphology and micro-roughness composed of: Ti-15Zr, Ti-19.1Nb-8.8Zr, Ti-41.2Nb-6.1Zr, and Ti-25Hf-25Ta. The commercially pure Ti cp and Ti-6Al-4V were used as control samples. The alloys were initially mechanically characterized with a tensile test using a universal testing machine. The results showed the lowest elastic modulus for the Ti-25Hf-25Ta alloy. We implanted a total of six implants in the mandible (3) and maxilla (3) for each titanium alloy in six minipigs and evaluated their bone index contact (i.e., the percentage of new bone in contact with the metal-BIC%) after 3 and 6 weeks of implantation. The results showed higher BIC% for the dental implants with lowest elastic modulus, showing the importance of decreasing the elastic modulus of alloys for the successful osseointegration of dental implants.

Indexed as

dental implantlow elastic modulusosseointegrationtitanium alloys

Identifiers

PMID30934553
PMCPMC6472162
OpenAlexW2924986316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.